A Micro-flow Phantom for Superficial Micro-vasculature Imaging
A Micro-flow Phantom for Superficial Micro-vasculature Imaging
复制标题
用于浅表微血管成像的微流模型
DOI:
10.1088/1742-6596/2071/1/012054
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发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Saijo Y
中科院分区:
文献类型:
--
作者:
Bhatti A;Ishii T;Saijo Y
Visualization of cutaneous micro-vasculatures is a powerful approach assisting in the diagnosis of skin vascular disorders. These minute structures can be visualized by high-frequency ultrasound (HFUS) using ultrafast Doppler imaging. Ultrasound flow phantoms have been used as assessment tools to evaluate the performance of the ultrasound imaging system, however, to optimize the imaging system for visualization of micro-structures, flow phantom with micro-channels is required which are usually difficult to fabricate. Here, we design a simple approach for micro-flow phantom which is easy to fabricate and cast for detection of micro-circulation in superficial micro-structures. The proposed approach features (i) the micro-channels of 200-micron at the depth of 4 mm (ii) casted in the cryogel mixture of Poly-vinyl alcohol (PVA) and (iii) infused at flow speed of 30 mm/s using infusion pump. Visualization of micro-flow channel in power Doppler image obtained by HFUS ultrafast Doppler imaging reveals that the proposed micro-flow phantom could serve as a viable assessment tool for optimizing the system for in-vivo cutaneous micro-vasculature imaging.
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--
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