Altered fractional amplitude of low-frequency fluctuation in women with premenstrual syndrome via acupuncture at Sanyinjiao (SP6).
Altered fractional amplitude of low-frequency fluctuation in women with premenstrual syndrome via acupuncture at Sanyinjiao (SP6).
复制标题
通过针刺三阴交（SP6）改变经前综合症女性低频波动的分数幅度。
DOI：
10.1186/s12991-021-00349-z
复制
发表时间：
2021-05-08
影响因子：
3.7
通讯作者：
Deng D
中科院分区：
文献类型：
--
作者：
Duan G;Chen Y;Pang Y;Feng Z;Liao H;Liu H;Zou Z;Li M;Tao J;He X;Li S;Liu P;Deng D
经前期综合征（PMS）是一种常见的妇科疾病，与神经活动异常密切相关.针灸是临床上治疗经前综合征的有效方法。然而，很少有研究已经进行了调查，是否针灸可能会调节异常的神经活动在PMS患者。因此，本研究的目的是评估经前综合征患者针刺刺激引起的脑活动的变化。本研究入组了20例PMS患者。所有患者均于月经黄体晚期电针刺激三阴交穴前后行静息态功能磁共振成像（rs-fMRI）检查。应用低频波动分数幅值（fALFF）方法检测经前综合征患者EAS相关脑改变。与EAS前比较，SP 6诱导的脑干、右侧丘脑、双侧丘脑、右侧中央旁小叶、双侧小脑等脑区fALFF值升高，而左侧楔叶、右侧楔前叶、左侧颞下皮质fALFF值降低。我们的研究结果提供了成像证据，支持SP 6相关的针刺刺激可能会调节经前综合症患者的神经活动。本研究可部分解释临床上针刺SP 6治疗PMS的神经机制。试验注册：本研究在http://www.chictr.org.cn上注册。临床试验注册号为ChiCTR-OPC-15005918，注册日期为2015年1月29日。
Premenstrual syndrome (PMS) is a prevalent gynecological disease and is significantly associated with abnormal neural activity. Acupuncture is an effective treatment on PMS in clinical practice. However, few studies have been performed to investigate whether acupuncture might modulate the abnormal neural activity in patients with PMS. Thereby, the aim of the study was to assess alterations of the brain activity induced by acupuncture stimulation in PMS patients. Twenty PMS patients were enrolled in this study. All patients received a 6-min resting-state functional magnetic resonance imaging (rs-fMRI) scan before and after electro-acupuncturing stimulation (EAS) at Sanyinjiao (SP6) acupoint in the late luteal phase of menstrual. Fractional amplitude of low-frequency fluctuation (fALFF) method was applied to examine the EAS-related brain changes in PMS patients. Compared with pre-EAS at SP6, increased fALFF value in several brain regions induced by SP6, including brainstem, right thalamus, bilateral insula, right paracentral lobule, bilateral cerebellum, meanwhile, decreased fALFF in the left cuneus, right precuneus, left inferior temporal cortex. Our findings provide imaging evidence to support that SP6-related acupuncture stimulation may modulate the neural activity in patients with PMS. This study may partly interpret the neural mechanisms of acupuncture at SP6 which is used to treat PMS patients in clinical. Trial registration: The study was registered on http://www.chictr.org.cn. The Clinical Trial Registration Number is ChiCTR-OPC-15005918, registry in 29/01/2015.
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影响因子：
2
作者：
Halbreich, Uriel;Backstrom, Torbjorn;Yonkers, Kimberly
通讯作者：
Yonkers, Kimberly
DOI：
10.1016/j.aat.2013.06.011
发表时间：
2013-06-01
期刊：
Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists
影响因子：
--
作者：
Yen, Chen-Tung;Lu, Pen-Li
通讯作者：
Lu, Pen-Li
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影响因子：
3
作者：
Zou, Qi-Hong;Zhu, Chao-Zhe;Zang, Yu-Feng
通讯作者：
Zang, Yu-Feng
影响因子：
--
作者：
Hui, Kathleen K S;Nixon, Erika E;Kennedy, David N
通讯作者：
Kennedy, David N
影响因子：
7.4
作者：
Lee, Mi Ji;Park, Bo-yong;Chung, Chin-Sang
通讯作者：
Chung, Chin-Sang