Racial disparities in symptomatology and outcomes of COVID-19 among adults of Arkansas.

Racial disparities in symptomatology and outcomes of COVID-19 among adults of Arkansas.
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DOI:
10.1016/j.pmedr.2022.101840
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发表时间:
2022-08
影响因子:
2.8
通讯作者:
Nembhard, Wendy N.
Nembhard, Wendy N.
中科院分区:
医学3区
文献类型:
--
作者:
Patel, Jenil R.;Amick, Benjamin C.;Vyas, Keyur S.;Bircan, Emine;Boothe, Danielle;Nembhard, Wendy N.

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很少有报告表明非西班牙裔黑人可能会出现与非西班牙裔白人不同的 COVID-19 症状。在这项由阿肯色州 60,000 多名不同种族成年人群体的代表性样本组成的新颖研究中,我们调查了 COVID-19 的症状和结果模式。我们发现不同种族/族裔之间的 COVID-19 症状存在差异,与新罕布什尔州白人相比,新罕布什尔州黑人和西班牙裔受影响更大,有特定或全部症状。承认临床环境中症状表现的差异将有助于准确诊断 COVID-19 患者。很少有报告表明非西班牙裔 (NH) 黑人可能会出现与 NH 白人不同的 COVID-19 症状。本研究的目的是调查阿肯色州成年人按种族/族裔划分的症状学模式和 COVID-19 结果。有关 COVID-19 症状的数据是在测试当天、第 7 天和第 14 天在阿肯色州各地的 UAMS 移动测试单位的参与者中收集的。通过鼻咽拭子和 RT-PCR 方法确诊 SARS-CoV-2 感染。使用卡方检验和泊松回归进行数据分析,以评估种族/民族特征的差异。 2020年3月29日至2020年10月7日,共有60,648人接受了RT-PCR检测。在检测呈阳性的成年人中,除了呼吸短促之外,西班牙裔比新罕布什尔州白人或新罕布什尔州黑人更有可能报告所有症状。新罕布什尔州白人更有可能报告发烧(19.6% vs. 16.6%)、咳嗽(27.5% vs. 26.1%)、呼吸短促(13.6% vs. 9.6%)、喉咙痛(16.7% vs. 10.7%)、寒战(12.5% vs. 11.8%)、肌肉疼痛(15.6% vs. 15.6% vs. 9.6%)。 12.4%)和头痛(20.3% vs. 17.8%)。 NH-黑人更有可能报告味觉/嗅觉丧失(10.9% vs. 10.6%)。总而言之,我们发现不同种族/民族的 COVID-19 症状存在差异,与新罕布什尔州白人相比,新罕布什尔州黑人和西班牙裔更容易出现特定或全部症状。由于横断面研究设计,这些发现不一定反映种族/民族的生物学差异;然而,他们认为某些种族/民族的健康状况可能存在潜在差异,从而影响 COVID-19 的结果。
Few reports have suggested that non-Hispanic Blacks may present with different symptoms for COVID-19 than non-Hispanic Whites. In this novel study comprising of representative sample of over 60,000 racially diverse population of Arkansas adults, we investigated patterns in symptomatology and outcomes of COVID-19. We found differences in COVID-19 symptoms by race/ethnicity, with NH-blacks and Hispanics affected more, with specific or all symptoms, compared to NH-whites. Acknowledging differences in presentation in symptoms at clinical setting will aid in accurate diagnoses of patients that present with COVID-19. Few reports have suggested that non-Hispanic (NH) blacks may present with different symptoms for COVID-19 than NH-whites. The objective of this study was to investigate patterns in symptomatology and COVID-19 outcomes by race/ethnicity among adults in Arkansas. Data on COVID-19 symptoms were collected on day of testing, 7th and 14th day among participants at UAMS mobile testing units throughout the state of Arkansas. Diagnosis for SARS-CoV-2 infection was confirmed via nasopharyngeal swab and RT-PCR methods. Data analysis was conducted using Chi-square test and Poisson regression to assess the differences in characteristics by race/ethnicity. A total of 60,648 individuals were RT-PCR tested from March 29, 2020 through October 7, 2020. Among adults testing positive, except shortness of breath, Hispanics were more likely to report all symptoms than NH-whites or NH-blacks. NH-whites were more likely to report fever (19.6% vs. 16.6%), cough (27.5% vs. 26.1%), shortness of breath (13.6% vs. 9.6%), sore throat (16.7% vs. 10.7%), chills (12.5% vs. 11.8%), muscle pain (15.6% vs. 12.4%), and headache (20.3% vs. 17.8%). NH-blacks were more likely to report loss of taste/smell (10.9% vs. 10.6%). To conclude, we found differences in COVID-19 symptoms by race/ethnicity, with NH-blacks and Hispanics more often affected with specific or all symptoms, compared to NH-whites. Due to the cross-sectional study design, these findings do not necessarily reflect biological differences by race/ethnicity; however, they suggest that certain race/ethnicities may have underlying differences in health status that impact COVID-19 outcomes.
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