Covid-19 Mortality: A Matter of Vulnerability Among Nations Facing Limited Margins of Adaptation.
Covid-19 Mortality: A Matter of Vulnerability Among Nations Facing Limited Margins of Adaptation.
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Covid-19死亡率：面临有限适应边界的国家之间的脆弱性问题。
DOI：
10.3389/fpubh.2020.604339
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发表时间：
2020
影响因子：
5.2
通讯作者：
Toussaint JF
中科院分区：
文献类型：
--
作者：
De Larochelambert Q;Marc A;Antero J;Le Bourg E;Toussaint JF
背景：人类发展领域在 Covid-19 大流行期间受到严重限制。人们观察到了一种共同的动态，但其在各个大陆的传播并不均匀。我们的目的是描述与死亡率最相关的非病毒参数。方法：我们通过主成分分析和皮尔逊相关性检验的相关矩阵，测试了 2020 年前 8 个月内五个领域（人口、公共卫生、经济、政治、环境）的主要指数及其与 Covid-19 死亡率的潜在关联。所有国家或联邦国家各州的数据均显示至少 10 起死亡病例，均来自官方公共网站。对于尚未结束第一流行阶段的国家，已经计算了一个前瞻性模型，以提供死亡率演变的选择。结果：在纬度 [25/65°] 和经度 [−35/−125°] 范围内观察到较高的新冠死亡率。与死亡率最相关的国家标准是预期寿命及其放缓、公共卫生背景（代谢和非传染性疾病（NCD）负担与传染病患病率）、经济（国民生产总值增长、财政支持）和环境（温度、紫外线指数）。为抗击流行病而采取的严格措施（包括封锁）似乎与死亡率无关。结论：预期寿命已经停滞或倒退、收入和非传染性疾病发病率较高的国家所付出的代价最高。更严格的公共决定并没有减轻这一负担。固有因素决定了 Covid-19 的死亡率：了解这些因素可以通过更好的身体健康和免疫力来提高人口的适应能力，从而改善预防策略。
Context: The human development territories have been severely constrained under the Covid-19 pandemic. A common dynamics has been observed, but its propagation has not been homogeneous over each continent. We aimed at characterizing the non-viral parameters that were most associated with death rate. Methods: We tested major indices from five domains (demography, public health, economy, politics, environment) and their potential associations with Covid-19 mortality during the first 8 months of 2020, through a Principal Component Analysis and a correlation matrix with a Pearson correlation test. Data of all countries, or states in federal countries, showing at least 10 fatality cases, were retrieved from official public sites. For countries that have not yet finished the first epidemic phase, a prospective model has been computed to provide options of death rates evolution. Results: Higher Covid death rates are observed in the [25/65°] latitude and in the [−35/−125°] longitude ranges. The national criteria most associated with death rate are life expectancy and its slowdown, public health context (metabolic and non-communicable diseases (NCD) burden vs. infectious diseases prevalence), economy (growth national product, financial support), and environment (temperature, ultra-violet index). Stringency of the measures settled to fight pandemia, including lockdown, did not appear to be linked with death rate. Conclusion: Countries that already experienced a stagnation or regression of life expectancy, with high income and NCD rates, had the highest price to pay. This burden was not alleviated by more stringent public decisions. Inherent factors have predetermined the Covid-19 mortality: understanding them may improve prevention strategies by increasing population resilience through better physical fitness and immunity.
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影响因子：
34.3
作者：
Baqui, Pedro;Bica, Ioana;van der Schaar, Mihaela
通讯作者：
van der Schaar, Mihaela
影响因子：
13.6
作者：
Chaix, B;Chauvin, P
通讯作者：
Chauvin, P
生物学定律：为什么这么少？
DOI：
10.1007/s11693-009-9049-0
发表时间：
2010-03
期刊：
Systems and synthetic biology
影响因子：
--
作者：
Dhar, Pawan K;Giuliani, Alessandro
通讯作者：
Giuliani, Alessandro
影响因子：
158.5
作者：
Olshansky, SJ;Passaro, DJ;Ludwig, DS
通讯作者：
Ludwig, DS
DOI：
10.1001/jama.2020.6775
发表时间：
2020-01-01
期刊：
JAMA, Journal of the American Medical Association
影响因子：
--
作者：
Richardson, Safiya;Hirsch, Jamie S.;,
通讯作者：
,