Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts.
Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts.
复制标题
DOI：
10.1016/j.jaad.2011.06.032
复制
发表时间：
2012-03
影响因子：
13.8
通讯作者：
Werth, Victoria P.
中科院分区：
文献类型：
--
作者：
Murrell, Dedee F.;Daniel, Benjamin S.;Joly, Pascal;Borradori, Luca;Amagai, Masayuki;Hashimoto, Takashi;Caux, Frederic;Marinovic, Branka;Sinha, Animesh A.;Hertl, Michael;Bernard, Philippe;Sirois, David;Cianchini, Giuseppe;Fairley, Janet A.;Jonkman, Marcel F.;Pandya, Amit G.;Rubenstein, David;Zillikens, Detlef;Payne, Aimee S.;Woodley, David;Zambruno, Giovanna;Aoki, Valeria;Pincelli, Carlo;Diaz, Luis;Hall, Russell P.;Meurer, Michael;Mascaro, Jose M., Jr.;Schmidt, Enno;Shimizu, Hiroshi;Zone, John;Swerlick, Robert;Mimouni, Daniel;Culton, Donna;Lipozencic, Jasna;Bince, Benjamin;Grando, Sergei A.;Bystryn, Jean-Claude;Werth, Victoria P.
近年来，我们对大疱性类天疱疮（BP）的科学认识有了很大的进步。然而，尽管有各种治疗炎症性疾病的治疗选择，只有少数多中心对照试验有助于确定BP的有效治疗方法。在共享多中心为基础的证据的治疗努力的一个主要障碍是缺乏普遍接受的定义，BP患者的临床评价。需要BP的通用术语和终点，以便该领域的专家能够准确地测量和评估疾病的范围，活动，严重程度和治疗反应，从而促进和推进临床试验。国际类天疱疮委员会的这些建议代表了2年的合作努力，以获得相互接受的BP共同定义，并提出了疾病程度评分，BP疾病面积指数。这些项目应有助于在未来的BP报告和研究中制定一致的结果报告。
Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sharing multicenter-based evidences for therapeutic efforts is the lack of generally accepted definitions for the clinical evaluation of patients with BP. Common terms and end points of BP are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. These recommendations from the International Pemphigoid Committee represent 2 years of collaborative efforts to attain mutually acceptable common definitions for BP and proposes a disease extent score, the BP Disease Area Index. These items should assist in the development of consistent reporting of outcomes in future BP reports and studies.
登录
查看更多内容
DOI：
10.1038/jid.2009.72
发表时间：
2009-10
期刊：
The Journal of investigative dermatology
影响因子：
--
作者：
通讯作者：
--
影响因子：
--
作者：
BERNARD, P;VAILLANT, L;PROST, C
通讯作者：
PROST, C
影响因子：
6.5
作者：
Joly, Pascal;Roujeau, Jean-Claude;Bernard, Philippe
通讯作者：
Bernard, Philippe
影响因子：
158.5
作者：
Joly, P;Roujeau, JC;Bernard, P
通讯作者：
Bernard, P
影响因子：
13.8
作者：
Murrell, Dedee E.;Dick, Sarah;Werth, Victoria P.
通讯作者：
Werth, Victoria P.