Profile of Patients with Novel Coronavirus Disease 2019 (COVID-19) in Osaka Prefecture, Japan: A Population-Based Descriptive Study.
Profile of Patients with Novel Coronavirus Disease 2019 (COVID-19) in Osaka Prefecture, Japan: A Population-Based Descriptive Study.
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DOI：
10.3390/jcm9092925
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发表时间：
2020-09-10
影响因子：
3.9
通讯作者：
Shimazu T
中科院分区：
文献类型：
--
作者：
Takeuchi T;Imanaka T;Katayama Y;Kitamura T;Sobue T;Shimazu T
日本2019冠状病毒病（COVID-19）患者的流行病学特征知之甚少。这是一项针对COVID-19患者的回顾性观察性研究；研究于2020年2月1日至5月31日进行。我们使用了日本大阪府通过聚合酶链反应（PCR）检测确诊的COVID-19病例公开收集的数据。我们描述了病人的特征。采用Cox比例风险模型评价因素（性别、发病月份、年龄组、居住城市）与死亡率的相关性，估计95%置信区间的风险比（hr）。在研究期间，5.7%（1782/ 31152）的人接受了COVID-19 PCR检测，结果呈阳性。在244例有症状信息的患者中，最常见的症状是发烧（76.6%），其次是咳嗽（44.3%）。在1782名患者中，86名患者死亡。与0 ~ 59岁相比，60 ~ 69岁（HR: 12.02[3.37 ~ 42.93]）、70 ~ 79岁（HR: 44.62[15.16 ~ 131.30]）、80 ~ 89岁（HR: 68.38[22.93 ~ 203.89]）和≥90岁（HR: 144.71[42.55 ~ 492.15]）患者的死亡率较高。总之，在日本大阪府，最常见的症状是发烧，老年人在COVID-19患者中的死亡率更高。
Little is known about the epidemiological characteristics of patients with coronavirus disease 2019 (COVID-19) in Japan. This is a retrospective observational study of COVID-19 patients; study was conducted from February 1 to May 31, 2020. We used publicly collected data on cases of COVID-19 confirmed by polymerase chain reaction (PCR) testing in Osaka Prefecture, Japan. We described the patient characteristics. The Cox proportional-hazards model was applied to evaluate the association between factors (sex, onset month, age group, city of residence) and mortality, and hazard ratios (HRs) with 95% confidence intervals were estimated. During the study period, 5.7% (1782/31,152) of individuals who underwent PCR testing for COVID-19 showed positive results. Among 244 patients with information on symptoms, the most common symptom was fever (76.6%), followed by cough (44.3%). Of the 1782 patients, 86 patients died. Compared with those aged 0–59 years, higher mortality was observed among those aged 60–69 years (HR: 12.02 [3.37–42.93]), 70–79 years (HR: 44.62 [15.16–131.30]), 80–89 years (HR: 68.38 [22.93–203.89]), and ≥90 years (HR: 144.71 [42.55–492.15]). In conclusion, in Osaka Prefecture, Japan, the most common symptom was fever, and older adults had higher mortality among COVID-19 patients.
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影响因子：
34.3
作者：
Baqui, Pedro;Bica, Ioana;van der Schaar, Mihaela
通讯作者：
van der Schaar, Mihaela
影响因子：
11.1
作者：
Imam, Z.;Odish, F.;Halalau, A.
通讯作者：
Halalau, A.
影响因子：
36.4
作者：
Goetzinger, Florian;Santiago-Garcia, Begona;Tebruegge, Marc
通讯作者：
Tebruegge, Marc
DOI：
10.1016/j.cca.2020.06.051
发表时间：
2020-11
期刊：
Clinica chimica acta; international journal of clinical chemistry
影响因子：
--
作者：
Wang M;Zhang J;Ye D;Wang Z;Liu J;He H;Shen B;Luo Z;Ye J;Xu Y;Zhao M;Liu M;Zhang P;Gu J;Pan W;Liu M;Li D;Wan J
通讯作者：
Wan J
影响因子：
56.3
作者：
To, Kelvin Kai-Wang;Tsang, Owen Tak-Yin;Yuen, Kwok-Yung
通讯作者：
Yuen, Kwok-Yung