Benzophenones and biflavonoids from Rheedia edulis.
Benzophenones and biflavonoids from Rheedia edulis.
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DOI：
10.1021/np100322d
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发表时间：
2010-11-29
影响因子：
5.1
通讯作者：
Kennelly EJ
中科院分区：
文献类型：
--
作者：
Acuña UM;Figueroa M;Kavalier A;Jancovski N;Basile MJ;Kennelly EJ
从黄芪种子和果皮中分离得到了2个新的聚异戊烯基化二苯甲酮，32-羟基- -guttiferone M(1)和6- epttiferone J(2)，以及7个已知化合物，6-epi-clusianone(3)、guttiferone A(4)、xanthochymol(5)、guttiferone E(6)、isoxanthochymol(7)、(+)-volkensiflavone(8)和(+)-morelloflavone(9)。其中化合物1 ~ 3和5 ~ 9为首次从该植物中分离得到。新化合物的结构主要通过分析它们的一维和二维核磁共振光谱数据来确定，它们的绝对构型是通过它们的实验旋光度和电子圆二色性测量值与DFT计算预测值的比较来确定的。化合物1在DPPH和ABTS自由基清除实验中均表现出显著的抗氧化活性，而化合物2则无活性。
Two new polyisoprenylated benzophenones, 32-hydroxy-ent-guttiferone M (1) and 6-epi-guttiferone J (2), along with seven known compounds, 6-epi-clusianone (3), guttiferone A (4), xanthochymol (5), guttiferone E (6), isoxanthochymol (7), (+)-volkensiflavone (8), and (+)-morelloflavone (9), were identified from the seeds and rinds of Rheedia edulis. Compounds 1-3 and 5-9 have been isolated and identified from the species for the first time. The structures of the new compounds were elucidated mainly by analysis of their 1D and 2D NMR spectroscopic data and their absolute configurations were determined by comparison of their experimental optical rotation and electronic circular dichroism measurements with those values predicted by DFT calculations. Compound 1 showed significant antioxidant activity in both DPPH and ABTS free radical scavenging assays, whereas compound 2 was inactive.
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影响因子：
3.3
作者：
Kolodziejczyk, Joanna;Masullo, Milena;Wachowicz, Barbara
通讯作者：
Wachowicz, Barbara
影响因子：
4.4
作者：
Furche, F
通讯作者：
Furche, F
影响因子：
6.1
作者：
Masullo, Milena;Bassarello, Carla;Piacente, Sonia
通讯作者：
Piacente, Sonia
影响因子：
5.1
作者：
Baggett, S;Protiva, P;Kennelly, EJ
通讯作者：
Kennelly, EJ
影响因子：
2.1
作者：
Masullo, Milena;Bassarello, Carla;Piacente, Sonia
通讯作者：
Piacente, Sonia