A unified framework for inhibitory control.
A unified framework for inhibitory control.
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DOI:
10.1016/j.tics.2011.07.011
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发表时间:
2011-10
影响因子:
19.9
通讯作者:
O'Reilly, Randall C.
中科院分区:
文献类型:
--
作者:
Munakata, Yuko;Herd, Seth A.;Chatham, Christopher H.;Depue, Brendan E.;Banich, Marie T.;O'Reilly, Randall C.
Inhibiting unwanted thoughts, actions and emotions figures centrally in daily life, and the prefrontal cortex is widely viewed as a source of this inhibitory control. We argue that the function of the prefrontal cortex is best understood in terms of representing and actively maintaining abstract information such as goals, which produces two types of inhibitory effects on other brain regions. Inhibition of some subcortical regions takes a directed, global form, with prefrontal regions providing contextual information relevant to when to inhibit all processing in a region. Inhibition within neocortical (and some subcortical) regions takes an indirect, competitive form, with prefrontal regions providing excitation of goal-relevant options. These distinctions are critical for understanding the mechanisms of inhibition and how they can be impaired or improved.
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