Co-Benefits of Largescale Organic farming On huMan health (BLOOM): Protocol for a cluster-randomised controlled evaluation of the Andhra Pradesh Community-managed Natural Farming programme in India.
Co-Benefits of Largescale Organic farming On huMan health (BLOOM): Protocol for a cluster-randomised controlled evaluation of the Andhra Pradesh Community-managed Natural Farming programme in India.
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DOI：
10.1371/journal.pone.0281677
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发表时间：
2023
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
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作者：
BLOOM研究（大规模有机农业对人类健康的共同利益）旨在确定政府实施的农业生态学计划是否减少了农药暴露并改善了农业家庭的饮食多样性。为了实现这一目标，将在印度南部安得拉邦四个地区的80个集群（40个干预和40个对照）中对安得拉邦社区管理的自然农业（APCNF）方案进行基于社区的随机分组对照评价。每个群组将随机挑选大约34个家庭进行筛选，并在基线时纳入评价。基线评估后12个月测量的两个主要结果是15%参与者随机子样本中的尿液农药代谢物和所有参与者的饮食多样性。两个主要结局将在入组时测量（1）≥18岁的成年男性，（2）≥18岁的成年女性和（3）<38个月的儿童。在同一家庭中测量的次要结果包括作物产量、家庭收入、成人人体测量、贫血、高血压、肾功能、肌肉骨骼疼痛、临床症状、抑郁症状、妇女赋权以及儿童生长和发育。分析将在意向治疗的基础上进行，并进行先验二次分析，以估计APCNF对结局的符合方案影响。BLOOM研究将提供强有力的证据，证明政府实施的大规模转型农业生态方案对农业家庭农药暴露和饮食多样性的影响。它还将提供采用农业生态学的营养，发展和健康共同效益的第一个证据，包括营养不良以及常见的慢性病。试验注册：研究注册：ISRCTN 11819073（https：//doi.org/10.1186/ISRCTN11819073）。印度临床试验注册中心CTRI/2021/08/035434。
The BLOOM study (co-Benefits of Largescale Organic farming On huMan health) aims to determine if a government-implemented agroecology programme reduces pesticide exposure and improves dietary diversity in agricultural households. To achieve this aim, a community-based, cluster-randomised controlled evaluation of the Andhra Pradesh Community-managed Natural Farming (APCNF) programme will be conducted in 80 clusters (40 intervention and 40 control) across four districts of Andhra Pradesh state in south India. Approximately 34 households per cluster will be randomly selected for screening and enrolment into the evaluation at baseline. The two primary outcomes, measured 12 months post-baseline assessment, are urinary pesticide metabolites in a 15% random subsample of participants and dietary diversity in all participants. Both primary outcomes will be measured in (1) adult men ≥18 years old, (2) adult women ≥18 years old, and (3) children <38 months old at enrolment. Secondary outcomes measured in the same households include crop yields, household income, adult anthropometry, anaemia, glycaemia, kidney function, musculoskeletal pain, clinical symptoms, depressive symptoms, women’s empowerment, and child growth and development. Analysis will be on an intention-to-treat basis with an a priori secondary analysis to estimate the per-protocol effect of APCNF on the outcomes. The BLOOM study will provide robust evidence of the impact of a large-scale, transformational government-implemented agroecology programme on pesticide exposure and dietary diversity in agricultural households. It will also provide the first evidence of the nutritional, developmental, and health co-benefits of adopting agroecology, inclusive of malnourishment as well as common chronic diseases. Trial registration: Study registration: ISRCTN 11819073 (https://doi.org/10.1186/ISRCTN11819073). Clinical Trial Registry of India CTRI/2021/08/035434.
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DOI：
10.1186/s13690-021-00711-3
发表时间：
2021-12-03
期刊：
Archives of public health = Archives belges de sante publique
影响因子：
--
作者：
Fite MB;Assefa N;Mengiste B
通讯作者：
Mengiste B
DOI：
10.1097/jom.0000000000000875
发表时间：
2016-11
影响因子：
3.2
作者：
Arcury TA;Laurienti PJ;Chen H;Howard TD;Barr DB;Mora DC;Summers P;Quandt SA
通讯作者：
Quandt SA
影响因子：
15.8
作者：
Bliznashka L;Udo IE;Sudfeld CR;Fawzi WW;Yousafzai AK
通讯作者：
Yousafzai AK
影响因子：
2.5
作者：
Daniel M;Maulik PK;Kallakuri S;Kaur A;Devarapalli S;Mukherjee A;Bhattacharya A;Billot L;Thornicroft G;Praveen D;Raman U;Sagar R;Kant S;Essue B;Chatterjee S;Saxena S;Patel A;Peiris D
通讯作者：
Peiris D
影响因子：
8.3
作者：
Bliznashka L;Roy A;Jaacks LM
通讯作者：
Jaacks LM