Prostate cancer - major changes in the American Joint Committee on Cancer eighth edition cancer staging manual.
Prostate cancer - major changes in the American Joint Committee on Cancer eighth edition cancer staging manual.
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DOI：
10.3322/caac.21391
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发表时间：
2017-05-06
期刊：
影响因子：
--
通讯作者：
Lin DW
中科院分区：
文献类型：
--
作者：
Buyyounouski MK;Choyke PL;McKenney JK;Sartor O;Sandler HM;Amin MB;Kattan MW;Lin DW
第八版美国癌症联合委员会（AJCC）肿瘤-淋巴结-转移（TNM）分期手册已经更新和改进，以确保最高程度的临床相关性，并提高其在患者评估和临床研究中的实用性。主要变化包括：1)病理学上的器官局限性疾病现在被认为是pT2，不再根据受累程度或侧侧性进行细分；2)肿瘤分级现在包括Gleason评分（如第七版标准）和分级组（在第八版标准中引入）；3)预后阶段III组包括基于前列腺特异性抗原和Gleason/分级组状态的选择性器官局限性疾病；4)分期手册中包括2个统计预测模型。AJCC将继续批判性地分析新出现的前列腺癌生物标志物和工具，以确保患者和医生能够以最高的准确性和信心预测和指导治疗决策。
The eighth edition of the American Joint Committee on Cancer (AJCC) tumor-node-metastasis (TNM) Staging Manual has been updated and improved to ensure the highest degree of clinical relevance and to improve its utility for patient evaluation and clinical research. Major changes include: 1) pathologically organconfined disease is now considered pT2 and is no longer subclassified by extent of involvement or laterality, 2) tumor grading now includes both the Gleason score (as in the seventh edition criteria) and the grade group (introduced in the eighth edition criteria), 3) prognostic stage group III includes select, organ-confined disease based on prostate-specific antigen and Gleason/grade group status, and 4) 2 statistical prediction models are included in the staging manual. The AJCC will continue to critically analyze emerging prostate cancer biomarkers and tools for their ability to prognosticate and guide treatment decision making with the highest level of accuracy and confidence for patients and physicians.
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影响因子：
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作者：
Reyes DK;Pienta KJ
通讯作者：
Pienta KJ
影响因子：
2.6
作者：
Lindenberg L;Choyke P;Dahut W
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Dahut W
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通讯作者：
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10.3
作者：
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通讯作者：
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影响因子：
--
作者：
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通讯作者：
Montironi, R