Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions.
Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions.
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DOI：
10.1016/j.ijid.2017.02.018
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发表时间：
2017-05
期刊：
影响因子：
--
通讯作者：
Jeffries R
中科院分区：
文献类型：
--
作者：
Al-Abri SS;Abaidani IA;Fazlalipour M;Mostafavi E;Leblebicioglu H;Pshenichnaya N;Memish ZA;Hewson R;Petersen E;Mala P;Nhu Nguyen TM;Rahman Malik M;Formenty P;Jeffries R
该文件全面概述了世界卫生组织东地中海区域（WHO EMR）各国的克里米亚-刚果出血热（CCHF）状况。本区域慢性充血性心力衰竭发病率的增加及其向新的地理区域的蔓延得到了强调。确定了WHO EMR中有关CCHF病毒负担和传播的知识差距。描述了一个战略框架，其中详细说明了必要的研究和开发工作，以遏制CCHF病毒造成的持续和新的威胁。克里米亚-刚果出血热（CCHF）是影响人类的最广泛的蜱传病毒性疾病。这种疾病在许多地区流行，如非洲、亚洲、东欧和南欧以及中亚。最近，CCHF的发病率在世界卫生组织东地中海区域（WHO EMR）国家迅速增加，该区域一些国家报告了CCHF的散发人间病例和暴发。尽管该疾病的发病率迅速增长，但由于这些国家对CCHF使用不同的监测系统，目前没有关于该区域疾病负担的准确数据。为了提高我们对世卫组织EMR中CCHF病毒（CCHFV;布尼亚病毒科的一种内罗毕病毒）传播的流行病学和风险因素的理解，并确定目前阻碍有效控制干预措施的知识差距，2015年12月7日至9日在阿曼麝香组织了一次区域会议。本文总结了该地区目前对该病的认识，确定了对预防和控制CCHFV提出挑战的知识差距，并详细介绍了遏制CCHFV造成的持续和新威胁所必需的研究和开发活动的战略框架。
The paper provides a comprehensive overview of the status of Crimean-Congo hemorrhagic fever (CCHF) in countries across the World Health Organization Eastern Mediterranean Region (WHO EMR). The increasing incidence of CCHF disease in the region and its spread to new geographical areas is highlighted. Knowledge gaps concerning the burden and circulation of CCHF virus in the WHO EMR are identified. A strategic framework is described, which details the research and development work necessary to curb the ongoing and new threats posed by CCHF virus. Crimean-Congo haemorrhagic fever (CCHF) is the most widespread, tick-borne viral disease affecting humans. The disease is endemic in many regions, such as Africa, Asia, Eastern and Southern Europe, and Central Asia. Recently, the incidence of CCHF has increased rapidly in the countries of the World Health Organization Eastern Mediterranean Region (WHO EMR), with sporadic human cases and outbreaks of CCHF being reported from a number of countries in the region. Despite the rapidly growing incidence of the disease, there are currently no accurate data on the burden of the disease in the region due to the different surveillance systems used for CCHF in these countries. In an effort to increase our understanding of the epidemiology and risk factors for the transmission of the CCHF virus (CCHFV; a Nairovirus of the family Bunyaviridae) in the WHO EMR, and to identify the current knowledge gaps that are hindering effective control interventions, a sub-regional meeting was organized in Muscat, Oman, from December 7 to 9, 2015. This article summarizes the current knowledge of the disease in the region, identifies the knowledge gaps that present challenges for the prevention and control of CCHFV, and details a strategic framework for research and development activities that would be necessary to curb the ongoing and new threats posed by CCHFV.
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DOI：
10.1016/s0035-9203(97)90014-6
发表时间：
1997-09-01
影响因子：
2.2
作者：
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影响因子：
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作者：
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影响因子：
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