Photoreactivating enzyme induction in human lymphocytes.
Photoreactivating enzyme induction in human lymphocytes.
复制标题
人淋巴细胞中的光活化酶诱导。
DOI:
10.1111/j.1751-1097.1982.tb03847.x
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发表时间:
1982
影响因子:
3.3
通讯作者:
Castellani,A
中科院分区:
文献类型:
--
作者:
Sutherland,BM;Castellani,A
Photoreactivating enzyme (PRE) activity was determined in human lymphocytes cultured in the presence or absence of the mitogen phytohemagglutinin (PHA). Photoreactivating enzyme activity increased from 0 to 12pmol/mg/h in about 40 h in cells cultured in the presence of PHA; enzyme activity was unchanged in the absence of PHA. The kinetics of induction of PRE and of lactate dehydrogenase, a marker of mitogenic stimulation, were indistinguishable, indicating that PRE induction results from stimulation of transcription and translation by the mitogen, rather than a specific effect of the PHA on PRE production. The level of PRE was also higher in mouse lymphoblasts growing rapidly in RPMI 1640 medium than in the same cells growing more slowly in Dulbecco's medium.
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DOI:
10.1042/bj1250841
发表时间:
1971
期刊:
The Biochemical journal
影响因子:
--
作者:
P. F. Swann;P. Magee
通讯作者:
P. Magee
DOI:
10.1073/pnas.71.3.639
发表时间:
1974-01-01
影响因子:
11.1
作者:
GOTH, R;RAJEWSKY, MF
通讯作者:
RAJEWSKY, MF
影响因子:
64.8
作者:
P. Kleihues;G. Margison
通讯作者:
G. Margison
影响因子:
64.8
作者:
P. Swann;P. Magee;U. Mohr;G. Reznik;U. Green;D. Kaufman
通讯作者:
D. Kaufman
影响因子:
4.8
作者:
P. Karran;T. Lindahl
通讯作者:
T. Lindahl