Upper aerodigestive tract neurofunctional mechanisms: lifelong evolution and exercise.

Upper aerodigestive tract neurofunctional mechanisms: lifelong evolution and exercise.
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DOI:
10.1002/hed.21902
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发表时间:
2011-10
影响因子:
2.9
通讯作者:
Robbins, JoAnne
Robbins, JoAnne
中科院分区:
医学2区
文献类型:
--
作者:
Robbins, JoAnne

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上呼吸消化道--口腔、咽和喉--的转变在睡眠和清醒时起着进食、说话和呼吸的作用。这些维持生命的功能可以由共享某些神经解剖学网络同时保持单独的神经功能系统和网络结构的中枢神经感觉运动系统产生。根据目前可用的成像方式和最近出现的干预措施,讨论了目前对发育,成熟,潜在的神经相关因素和综合因素的理解。运动和一系列额外的治疗方法似乎为循证创新、新的阻滞和康复策略提供了有希望的转化途径,甚至可以预防神经肌肉功能的交叉下降,并在日益持久的寿命中支持生活质量。
The transformation of the upper aerodigestive tract – oral cavity, pharynx and larynx – serves the functions of eating, speaking and breathing during sleeping and waking hours. These life-sustaining functions may be produced by a central neural sensorimotor system that shares certain neuroanatomic networks while maintaining separate neural functional systems and network structures. Current understanding of development, maturation, underlying neural correlates and integrative factors are discussed in light of currently available imaging modalities and recently emerging interventions. Exercise and an array of additional treatments together appear to provide promising translational pathways for evidence-based innovation, novel habilitation and rehabilitation strategies and delay, or even prevent neuromuscular decline cross-cutting functions and supporting quality of life throughout increasingly enduring lifespans.
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