Placebo expectations and the detection of somatic information.
Placebo expectations and the detection of somatic information.
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DOI：
10.1007/s10865-010-9301-9
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发表时间：
2011-06
影响因子：
3.1
通讯作者：
Helfer SG
中科院分区：
文献类型：
--
作者：
Geers AL;Wellman JA;Fowler SL;Rasinski HM;Helfer SG
在一项实验室研究中，我们检验了一个假设，即安慰剂预期增强了对安慰剂相关感觉的初始识别，而不是安慰剂无关感觉。参与者（N = 102）被随机分配到三个期望组之一。在第一组中，参与者服用安慰剂胶囊，并被告知这是咖啡因（欺骗性期望）。在第二组中，参与者摄入安慰剂胶囊，并被告知它可能是咖啡因或安慰剂（双盲预期）。第三组的参与者没有任何期望。然后，所有参与者记录他们在7分钟内经历的安慰剂相关和安慰剂无关的感觉。欺骗性期望组的参与者识别出的安慰剂相关感觉比安慰剂无关感觉更多。无期望参与者识别出更多的安慰剂无关的感觉比安慰剂相关的感觉。给予双盲预期的参与者识别了等量的安慰剂相关和不相关的感觉。检测到的安慰剂相关和安慰剂无关的感觉的量介导了期望操纵和随后的症状报告之间的关系。这些数据支持这样一种观点，即期望在一定程度上是通过改变人们对身体感觉的识别来引起安慰剂反应的。
In a laboratory study we examined the hypothesis that placebo expectations enhance the initial identification of placebo-relevant sensations over placebo-irrelevant sensations. Participants (N = 102) were randomly assigned to one of three expectation groups. In the first group, participants ingested a placebo capsule and were told it was caffeine (deceptive expectation). In a second group, participants ingested a placebo capsule and were told it may be caffeine or it may be a placebo (double-blind expectation). Participants in the third group were given no expectation. All participants then tallied the placebo-relevant and placebo-irrelevant sensations they experienced during a 7-min period. Participants in the deceptive expectation group identified more placebo-relevant sensations than placebo-irrelevant sensations. No-expectation participants identified more placebo-irrelevant sensations than placebo-relevant sensations. Participants given the double-blind expectation identified an equal amount of placebo-relevant and irrelevant sensations. The amount of both placebo-relevant and placebo-irrelevant sensations detected mediated the relationship between the expectation manipulation and subsequent symptom reports. These data support the position that expectations cause placebo responding, in part, by altering how one identifies bodily sensations.
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影响因子：
4.6
作者：
DINNERSTEIN, AJ;HALM, J
通讯作者：
HALM, J
影响因子：
1.9
作者：
KIRSCH, I;WEIXEL, LJ
通讯作者：
WEIXEL, LJ
DOI：
10.1073/pnas.0408576102
发表时间：
2005-09-06
影响因子：
11.1
作者：
Koyama, T;McHaffie, JG;Coghill, RC
通讯作者：
Coghill, RC
影响因子：
3.1
作者：
Geers, AL;Helfer, SG;Kosbab, K
通讯作者：
Kosbab, K
影响因子：
56.9
作者：
de la Fuente-Fernández, R;Ruth, TJ;Stoessl, AJ
通讯作者：
Stoessl, AJ