Integrated photonic slow light Michelson interferometer bio sensor
Integrated photonic slow light Michelson interferometer bio sensor
复制标题
集成光子慢光迈克尔逊干涉仪生物传感器
DOI：
10.1117/12.2650514
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Chakravarty, Swapnajit
中科院分区：
文献类型：
--
作者：
Shen, Jianhao;Donnelly, Daniel;Chakravarty, Swapnajit
利用集成硅光子学的各种基于芯片的传感器已在谐振器和移相器/干涉仪配置中得到证明。迄今为止，使用马赫-曾德尔干涉仪（MZI）和杨氏干涉仪的干涉技术已经显示出最低的质量检测极限（pg/mm 2）。与MZI集成的光子晶体波导中的慢光由于光以高群折射率传播而增强的光程长度而实现紧凑的几何形状。在典型的MZI中，在信号臂中传播的光与分析物重叠，并且相对于参考臂中的光经历相对相位变化，这导致测量的输出强度变化。在本文中，使用集成的光子方法，我们展示了慢光增强迈克尔逊干涉仪（MI）生物传感器，其中的参考和信号臂被传播的光学模式穿过两次。结果，分析物相互作用长度有效地加倍，因为传播光学模式经历两倍于在MZI中观察到的相移。在非对称MI配置中，对于分析物浓度的固定变化，观察到相移的所得加倍作为共振波长偏移的加倍。因此，器件灵敏度相对于常规MZI加倍，同时与MZI传感器相比还有效地将几何长度减半。
Diverse chip-based sensors utilizing integrated silicon photonics have been demonstrated in resonator and phase shifter/interferometer configurations. Till date, interferometric techniques with the Mach-Zehnder Interferometer (MZI) and Young’s interferometer have shown the lowest mass detection limits (in pg/mm2). Slow light in photonic crystal waveguides integrated with MZIs enables compact geometries due to enhanced optical path lengths as light propagates with high group index. In a typical MZI, light propagating in the signal arm overlaps with analytes and undergo a relative phase change with respect to the light in the reference arm which leads to measured output intensity changes. In this paper, using integrated photonic methods, we demonstrate a slow light enhanced Michelson interferometer (MI) biosensor, wherein the reference and signal arms are traversed twice by the propagating optical mode. As a result, the analyte interaction length is effectively doubled since the propagating optical mode undergoes twice the phase shift as would be observed in a MZI. In an asymmetric MI configuration, the resultant doubling of the phase shift is observed as a doubling of the resonance wavelength shift for a fixed change in the analyte concentration. The device sensitivity is thus doubled with respect to a conventional MZI while also effectively halving the geometric length compared to the MZI sensor.
影响因子：
12.6
作者：
Chakravarty S;Lai WC;Zou Y;Drabkin HA;Gemmill RM;Simon GR;Chin SH;Chen RT
通讯作者：
Chen RT
影响因子：
4
作者：
Chakravarty, Swapnajit;Hosseini, Amir;Chen, Ray T.
通讯作者：
Chen, Ray T.