Efficacy Evaluation of Neurofeedback-Based Anxiety Relief.

Efficacy Evaluation of Neurofeedback-Based Anxiety Relief.
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基于神经反馈的焦虑缓解效果评估

DOI:
10.3389/fnins.2021.758068
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发表时间:
2021
影响因子:
4.3
通讯作者:
Ming D
Ming D
中科院分区:
医学2区
文献类型:
--
作者:
Chen C;Xiao X;Belkacem AN;Lu L;Wang X;Yi W;Li P;Wang C;Sha S;Zhao X;Ming D

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焦虑症是一种涉及极度恐惧或担忧的精神疾病,它会改变大脑中化学物质的平衡。这种焦虑状态的变化和评估伴随着综合治疗程序。众所周知,焦虑症的治疗主要以心理治疗和药物治疗为主,缺乏客观的标准评价。在本文中,所提出的方法的重点是检查神经的变化,探讨正念调节与焦虑患者的神经反馈的影响。我们设计了一个封闭的神经反馈实验,包括三个阶段来调整被试的心理状态。共有34名受试者参加了这项实验,其中17名焦虑症患者和17名健康人。通过实验的三个阶段,记录了静息状态下的脑电信号和正念状态下的脑电信号。通过神经反馈正念的调节作用,选取功率谱密度作为评价指标,采用重复方差分析方法进行统计分析。本研究的结果显示,所提出的方法对这两种类型的主题都有积极的影响。正念调整后,功率图呈上升趋势。γ波平均功率的增加表明焦虑的缓解。波功率的增强代表了受试者正念能力的提高。同时,方差分析结果显示P < 0.05,即,差异有统计学意义。从神经生理信号的角度,客观地评价了本实验缓解焦虑的能力。神经反馈正念调节可以影响焦虑症患者的脑活动模式。
Anxiety disorder is a mental illness that involves extreme fear or worry, which can alter the balance of chemicals in the brain. This change and evaluation of anxiety state are accompanied by a comprehensive treatment procedure. It is well-known that the treatment of anxiety is chiefly based on psychotherapy and drug therapy, and there is no objective standard evaluation. In this paper, the proposed method focuses on examining neural changes to explore the effect of mindfulness regulation in accordance with neurofeedback in patients with anxiety. We designed a closed neurofeedback experiment that includes three stages to adjust the psychological state of the subjects. A total of 34 subjects, 17 with anxiety disorder and 17 healthy, participated in this experiment. Through the three stages of the experiment, electroencephalography (EEG) resting state signal and mindfulness-based EEG signal were recorded. Power spectral density was selected as the evaluation index through the regulation of neurofeedback mindfulness, and repeated analysis of variance (ANOVA) method was used for statistical analysis. The findings of this study reveal that the proposed method has a positive effect on both types of subjects. After mindfulness adjustment, the power map exhibited an upward trend. The increase in the average power of gamma wave indicates the relief of anxiety. The enhancement of the wave power represents an improvement in the subjects’ mindfulness ability. At the same time, the results of ANOVA showed that P < 0.05, i.e., the difference was significant. From the aspect of neurophysiological signals, we objectively evaluated the ability of our experiment to relieve anxiety. The neurofeedback mindfulness regulation can effect on the brain activity pattern of anxiety disorder patients.
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DOI: 10.1007/s40846-020-00596-7
发表时间: 2021
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