Cognitive behavioral therapy for anxiety and related disorders: A meta-analysis of randomized placebo-controlled trials.
Cognitive behavioral therapy for anxiety and related disorders: A meta-analysis of randomized placebo-controlled trials.
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DOI：
10.1002/da.22728
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发表时间：
2018-06
影响因子：
7.4
通讯作者：
Hofmann SG
中科院分区：
文献类型：
--
作者：
Carpenter JK;Andrews LA;Witcraft SM;Powers MB;Smits JAJ;Hofmann SG
本研究的目的是基于随机安慰剂对照试验，检查认知行为疗法（CBT）对焦虑相关障碍的疗效。我们纳入了41项研究，这些研究将患有急性应激障碍、广泛性焦虑障碍（GAD）、强迫症（OCD）、惊恐障碍（PD）、创伤后应激障碍（PTSD）或社交焦虑障碍（SAD）的患者（N = 2，835）随机分配到CBT或心理或药丸安慰剂条件下。研究结果表明，CBT对目标障碍症状（Hedges' g = 0.56）有中度安慰剂对照效应，对其他焦虑症状（Hedges' g = 0.38）、抑郁（Hedges' g = 0.31）和生活质量（Hedges' g = 0.30）有小至中度效应。与安慰剂相比，CBT的应答率与2.97的比值比相关。在SAD和PTSD研究中，完成者样本对目标疾病的影响显著强于意向治疗样本，个体与CBT组相比。强迫症、广泛性焦虑症和急性应激障碍的效应量较大，创伤后应激障碍、SAD和PD的效应量较小至中等。在PTSD研究中，CBT组的脱落率（29.0%）高于安慰剂组（17.2%），但其他疾病的脱落率没有差异。主要使用暴露策略的干预措施比使用认知或认知和行为技术的干预措施具有更大的效应量，尽管这种差异没有达到显著性。研究结果表明，与安慰剂相比，CBT是一种中等有效的焦虑症治疗方法。特别需要更有效的治疗PTSD，SAD和PD。
The purpose of this study was to examine the efficacy of cognitive behavioral therapy (CBT) for anxiety-related disorders based on randomized placebo-controlled trials. We included 41 studies that randomly assigned patients (N = 2,835) with acute stress disorder, generalized anxiety disorder (GAD), obsessive compulsive disorder (OCD), panic disorder (PD), posttraumatic stress disorder (PTSD) or social anxiety disorder (SAD) to CBT or a psychological or pill placebo condition. Findings demonstrated moderate placebo-controlled effects of CBT on target disorder symptoms (Hedges’ g = 0.56), and small to moderate effects on other anxiety symptoms (Hedges’ g = 0.38), depression (Hedges’ g = 0.31) and quality of life (Hedges’ g = 0.30). Response rates in CBT compared to placebo were associated with an odds ratio of 2.97. Effects on the target disorder were significantly stronger for completer samples than intent-to-treat samples, and for individual compared to group CBT in SAD and PTSD studies. Large effect sizes were found for OCD, GAD and acute stress disorder, and small to moderate effect sizes were found for PTSD, SAD and PD. In PTSD studies, dropout rates were greater in CBT (29.0%) compared to placebo (17.2%), but no difference in dropout was found across other disorders. Interventions primarily using exposure strategies had larger effect sizes than those using cognitive or cognitive and behavioral techniques, though this difference did not reach significance. Findings demonstrate that CBT is a moderately efficacious treatment for anxiety disorders when compared to placebo. More effective treatments are especially needed for PTSD, SAD and PD.
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影响因子：
22.8
作者：
Cottraux, Jean;Note, Ivan;Chen, Yaohua
通讯作者：
Chen, Yaohua
影响因子：
5.9
作者：
Clark, DM;Ehlers, A;Louis, B
通讯作者：
Louis, B
影响因子：
6.9
作者：
Cuijpers, P.;Cristea, I. A.;Berking, M.
通讯作者：
Berking, M.
DOI：
10.1007/s10862-009-9161-1
发表时间：
2010-03
影响因子：
1.6
作者：
Cisler, Josh M.;Olatunji, Bunmi O.;Feldner, Matthew T.;Forsyth, John P.
通讯作者：
Forsyth, John P.
DOI：
10.1146/annurev-clinpsy-032813-153734
发表时间：
2014-01-01
期刊：
ANNUAL REVIEW OF CLINICAL PSYCHOLOGY, VOL 10
影响因子：
--
作者：
Beck, Aaron T.;Haigh, Emily A. P.
通讯作者：
Haigh, Emily A. P.