ZCURVE 3.0: identify prokaryotic genes with higher accuracy as well as automatically and accurately select essential genes.
ZCURVE 3.0: identify prokaryotic genes with higher accuracy as well as automatically and accurately select essential genes.
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ZCURVE 3.0:更准确地识别原核基因,自动准确选择必需基因
DOI:
10.1093/nar/gkv491
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发表时间:
2015-07-01
影响因子:
14.9
通讯作者:
Guo FB
中科院分区:
文献类型:
--
作者:
Hua ZG;Lin Y;Yuan YZ;Yang DC;Wei W;Guo FB
In 2003, we developed an ab initio program, ZCURVE 1.0, to find genes in bacterial and archaeal genomes. In this work, we present the updated version (i.e. ZCURVE 3.0). Using 422 prokaryotic genomes, the average accuracy was 93.7% with the updated version, compared with 88.7% with the original version. Such results also demonstrate that ZCURVE 3.0 is comparable with Glimmer 3.02 and may provide complementary predictions to it. In fact, the joint application of the two programs generated better results by correctly finding more annotated genes while also containing fewer false-positive predictions. As the exclusive function, ZCURVE 3.0 contains one post-processing program that can identify essential genes with high accuracy (generally >90%). We hope ZCURVE 3.0 will receive wide use with the web-based running mode. The updated ZCURVE can be freely accessed from http://cefg.uestc.edu.cn/zcurve/ or http://tubic.tju.edu.cn/zcurveb/ without any restrictions.
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影响因子:
14.9
作者:
Luo H;Lin Y;Gao F;Zhang CT;Zhang R
通讯作者:
Zhang R
影响因子:
14.9
作者:
Tatusova T;Ciufo S;Fedorov B;O'Neill K;Tolstoy I
通讯作者:
Tolstoy I
DOI:
10.1007/978-1-4939-2398-4_13
发表时间:
2015-01-01
期刊:
Methods in molecular biology (Clifton, N.J.)
影响因子:
--
作者:
Guo, Feng-Biao;Ye, Yuan-Nong;Wei, Wen
通讯作者:
Wei, Wen
影响因子:
7
作者:
Seringhaus, Michael;Paccanaro, Alberto;Gerstein, Mark
通讯作者:
Gerstein, Mark
影响因子:
9.5
作者:
Richardson EJ;Watson M
通讯作者:
Watson M