Emergence and pandemic potential of swine-origin H1N1 influenza virus.

Emergence and pandemic potential of swine-origin H1N1 influenza virus.
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DOI:
10.1038/nature08157
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发表时间:
2009-06-18
期刊:
影响因子:
64.8
通讯作者:
Kawaoka, Yoshihiro
Kawaoka, Yoshihiro
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Neumann, Gabriele;Noda, Takeshi;Kawaoka, Yoshihiro

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流感病毒引起每年的流行病和偶尔的大流行,夺去了数百万人的生命。新菌株的出现将继续对公共卫生和科学界构成挑战。一个主要的例子是最近出现的猪源H1N1病毒,这种病毒已经传播给人类并在人类之间传播,导致了国际性的疫情。努力控制这些疫情和实时监测这种病毒的演变应该为我们提供宝贵的信息,以指导传染病控制计划,并提高对决定病毒致病性和/或传播性的因素的理解。
Influenza viruses cause annual epidemics and occasional pandemics that have claimed the lives of millions. The emergence of novel strains will continue to pose challenges to the public health and scientific communities. A prime example is the recent emergence of swine-origin H1N1 viruses that have transmitted to and spread among humans, resulting in outbreaks internationally. Efforts to control these outbreaks and real-time monitoring of the evolution of this virus should provide us with invaluable information to direct infectious disease control programs and to improve understanding of the factors that determine viral pathogenicity and/or transmissibility.
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