Orientation perception in Williams Syndrome: discrimination and integration.
Orientation perception in Williams Syndrome: discrimination and integration.
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DOI：
10.1016/j.bandc.2008.11.007
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发表时间：
2009-06
影响因子：
2.5
通讯作者：
Egeth, Howard
中科院分区：
文献类型：
--
作者：
Palomares, Melanie;Landau, Barbara;Egeth, Howard
关键词：
Williams Syndrome (WS) is a rare neurodevelopmental disorder, which stems from a genetic deletion on chromosome 7 that causes a profound weakness in visuospatial cognition. Our current study explores how orientation perception may contribute to the visuospatial deficits in WS. In Experiment 1, we found that WS individuals and normal 3-4 year olds had similar orientation discrimination thresholds and had similar prevalence of mirror-reversal errors for diagonal targets (±45 deg). In Experiment 2, we asked whether this immaturity in orientation discrimination would also be reflected in a task requiring integration of oriented elements. We found that sensitivities of WS individuals for detecting orientation-defined contours were higher than sensitivities of normal 3-4 year olds, and were not significantly different from sensitivities of normal adults. Together, these results suggest that orientation discrimination and orientation integration have different maturational trajectories in normal development and different susceptibilities to damage in WS, which may reflect largely separate visuospatial mechanisms.
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