Persistence of type-specific human papillomavirus infection among Daqing City women in China with normal cytology: a pilot prospective study.
Persistence of type-specific human papillomavirus infection among Daqing City women in China with normal cytology: a pilot prospective study.
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中国大庆市细胞学正常女性中型特异性人乳头瘤病毒感染的持续性：一项试点前瞻性研究
DOI：
10.18632/oncotarget.20188
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发表时间：
2017-10-06
期刊：
影响因子：
--
通讯作者：
Dai M
中科院分区：
文献类型：
--
作者：
Li N;Hang D;Yang L;Feng X;Lyu Z;Xie S;Zhou J;Wu L;Li X;Li N;Cheng M;Zhang K;Zhang Z;Cui H;Yin J;Hu Z;Shen H;Dai M
Persistence of high-risk human papillomavirus (HPV) represents the necessary cause of cervical cancer. Researching natural history of HPV infection is important to identify high-risk population of cervical cancer. Since HPV infection is population-specific, the findings in western populations could not be simply extended to Chinese and Asian females. This study investigated the type-specific persistence of HPV and related factors among Daqing City women in China. A total of 1759 women aged 18–80 years were enrolled at baseline. Cervical cell specimens were collected for cytological examination and HPV detection. HPV-positive individuals with normal cytology were followed up after 12 months. The results showed that HPV prevalence was 8.64% at baseline, of which 85 HPV-positive cases with normal cytology were followed up. The one-year type-specific persistence of HPV and high-risk types were 34.12% (29/85) and 34.25% (25/73), respectively. The top three high-risk types were HPV16 (7/17, 41.18%), HPV18 (5/8, 62.50%) and HPV58 (7/15, 46.67%). Age > 50 years was significantly associated with a higher risk of HPV persistence compared to ≤ 50 (OR = 2.73; 95% CI: 1.07, 6.93). In conclusion, approximately one-third of Daqing City women with HPV infection had at least one-year viral persistence, most of which were high-risk types. Older age represents a risk factor of HPV persistence.
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影响因子：
51.1
作者：
de Sanjose, Silvia;Quint, Wim G. V.;Xavier Bosch, F.
通讯作者：
Xavier Bosch, F.
影响因子：
3.7
作者：
Schmeink CE;Melchers WJ;Siebers AG;Quint WG;Massuger LF;Bekkers RL
通讯作者：
Bekkers RL
中华人民共和国山西省的人乳头瘤病毒感染：一项基于人群的研究。
影响因子：
8.8
作者：
Dai, M;Bao, Y P;Li, N;Clifford, G M;Vaccarella, S;Snijders, P J F;Huang, R D;Sun, L X;Meijer, C J L M;Qiao, Y L;Franceschi, S
通讯作者：
Franceschi, S
DOI：
10.1136/bmj.e4168
发表时间：
2012-06-22
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Oakeshott P;Aghaizu A;Reid F;Howell-Jones R;Hay PE;Sadiq ST;Lacey CJ;Beddows S;Soldan K
通讯作者：
Soldan K
影响因子：
3.7
作者：
Ferreccio, Catterina;Van De Wyngard, Vanessa;Snijders, Peter J. F.
通讯作者：
Snijders, Peter J. F.