The obsessive-compulsive spectrum in the perinatal period: a prospective pilot study.

The obsessive-compulsive spectrum in the perinatal period: a prospective pilot study.
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DOI:
10.1007/s00737-010-0154-6
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发表时间:
2010-10
影响因子:
4.5
通讯作者:
Nirodi, Neha
Nirodi, Neha
中科院分区:
医学2区
文献类型:
--
作者:
Chaudron, Linda H.;Nirodi, Neha

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本研究旨在描述围产期妇女的强迫症状(OCS)和强迫症(OCD)现象,并探讨OCS/OCD与产后抑郁症的关系。一项前瞻性纵向研究,44名妇女筛选与强迫量表修订(OCI-R)和爱丁堡产后抑郁量表(EPDS)之间的30和37周的怀孕。24名妇女在分娩前完成了诊断性访谈和耶鲁-布朗强迫症量表(Y-BOCS),并在产后联系重复EPDS和Y-BOCS。在妊娠晚期,32%的人报告了高水平的焦虑和/或抑郁症状(EPDS≥10和/或OCI-R≥15),29%完成诊断访谈的人符合OCD标准。在产后1个月,12.5%有新的OCS(Y-BOCS≥8),25%有新的高水平抑郁症状(EPDS≥10)。OCS强度增加产后,但没有改变的性质。强迫症和强迫症可能是更大的患病率在围产期比以前认识到的。高发病率提供了新的信息,需要在更大、更多样化的人群中进行复制。围产期的研究必须超越抑郁症的探索,包括焦虑症,特别是强迫症。
This study aims to describe the phenomenology of obsessive–compulsive symptoms (OCS) and disorders (OCD) in perinatal women and to explore the relationship of OCS/OCD to postpartum depression. A prospective longitudinal study of 44 women screened with the Obsessive–Compulsive Inventory—Revised (OCI-R) and Edinburgh Postnatal Depression Scale (EPDS) between 30 and 37 weeks of pregnancy. Twenty-four women completed a diagnostic interview and the Yale–Brown Obsessive–Compulsive Scale (Y-BOCS) before delivery and were contacted postpartum to repeat the EPDS and Y-BOCS. In the third trimester, 32% reported high levels of anxiety and/or depressive symptoms (EPDS≥10 and/or OCI-R≥15) and 29% of those who completed the diagnostic interview met criteria for OCD. At 1 month postpartum, 12.5% had new OCS (Y-BOCS≥8) and 25% had new high levels of depressive symptoms (EPDS≥10). OCS increased in intensity postpartum but did not change in character. OCD and OCS may be of greater prevalence during the perinatal period than previously recognized. The high rates provide new information and require replication in larger, more diverse populations. Research in the perinatal period must expand beyond the exploration of depression to include anxiety disorders and specifically OCD.
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