Relation of depressive symptoms to outcome of CI movement therapy after stroke.
Relation of depressive symptoms to outcome of CI movement therapy after stroke.
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DOI：
10.1037/rep0000171
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发表时间：
2017-11
影响因子：
2.7
通讯作者：
Mark VW
中科院分区：
文献类型：
--
作者：
Haddad MM;Uswatte G;Taub E;Barghi A;Mark VW
卒中后抑郁症状与不良结局相关，包括功能能力较差、康复服务利用效率低下、生活质量下降和死亡率增加。有传闻指出，抑郁症状不会限制接受约束诱导运动疗法（CIMT）的患者的运动恢复，CIMT是一种有效的慢性卒中后轻偏瘫干预措施。在这里，我们分析了抑郁症状和运动得分从40名参与者谁收到CIMT在两个先前发表的研究。中风后超过1年的轻度至中度上肢轻偏瘫成年人在CIMT前后完成Zung抑郁自评量表和运动活动日志（MAL）。我们使用回归分析来测试Zung评分是否预测对CIMT的反应，并使用配对t检验来测试抑郁症状是否从治疗前到治疗后发生变化。在控制治疗前MAL评分后，治疗前Zung评分不能预测MAL组使用量表的结局，ΔR2（1，30）= 0.004，p = 0.19。此外，受试者的Zung评分略有下降，但具有统计学意义，t（39）= 3.0，p = 0.005，平均变化=-3.6。这些结果表明，抑郁症状并没有显着限制运动的恢复与CIMT治疗慢性中风后轻偏瘫患者。此外，CIMT治疗可以改善抑郁症状。
Depressive symptoms after stroke have been associated with negative outcomes, including poorer functional ability, less efficient use of rehabilitation services, decreased quality of life, and increased mortality. It has been anecdotally noted that depressive symptoms do not limit motor recovery in patients who undergo Constraint-Induced Movement therapy (CIMT), an efficacious intervention for chronic post-stroke hemiparesis. Here we analyze depressive symptom and motor scores from 40 participants who received CIMT in two previously published studies. Adults more than 1-year after stroke with mild to moderate upper-extremity hemiparesis completed the Zung Self-Rating Depression Scale and Motor Activity Log (MAL) before and after CIMT. We used regression analysis to test whether Zung scores predicted response to CIMT and paired t-tests to test whether depressive symptoms changed from pre- to post-treatment. Pre-treatment Zung score did not predict outcome on the MAL Arm Use scale, ΔR2 (1,30) = 0.004, p = .19, after controlling for pre-treatment MAL scores. Additionally, participants had a small but statistically significant decrease in Zung score, t(39) = 3.0, p = 0.005, mean change = −3.6. These results suggest that depressive symptoms do not significantly limit motor recovery in patients treated with CIMT for chronic post-stroke hemiparesis. Additionally, treatment with CIMT may improve depressive symptoms.
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