Virology, epidemiology, immunology and vaccine development of SARS-CoV-2, update after nine months of pandemic.
Virology, epidemiology, immunology and vaccine development of SARS-CoV-2, update after nine months of pandemic.
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DOI:
10.1016/j.biologicals.2020.11.003
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发表时间:
2021-01
期刊:
影响因子:
--
通讯作者:
Neels P
中科院分区:
文献类型:
--
作者:
Baay M;Lina B;Fontanet A;Marchant A;Saville M;Sabot P;Vandeputte J;Neels P
This International Alliance for Biological Standardization COVID-19 webinar was organized to provide an update on the virology, epidemiology and immunology of, and the vaccine development for SARS-CoV-2, none months after COVID-19 was declared a public health emergency of international concern. It brought together a broad range of international stakeholders, including academia, regulators, funders and industry, with a considerable delegation from low- and middle-income countries. Recombination probably led to a virus that acquired human-to-human transmissibility. Initially, SARS-CoV-2 infection in the second wave was mistakenly interpreted as more benign. Neutralizing antibodies likely contribute to control of SARS-CoV-2 disease. A mucosal immune response (IgA in nasal mucus or saliva) may be a useful correlate of protection. COVAX aims to deliver 2 billion doses of vaccine by the end of 2021, to all the countries around the world.
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DOI:
10.1126/science.abc6261
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期刊:
Science (New York, N.Y.)
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