Influencing food choices by training: evidence for modulation of frontoparietal control signals.
Influencing food choices by training: evidence for modulation of frontoparietal control signals.
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DOI：
10.1162/jocn_a_00495
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发表时间：
2014-02
影响因子：
3.2
通讯作者：
Poldrack RA
中科院分区：
文献类型：
--
作者：
Schonberg T;Bakkour A;Hover AM;Mumford JA;Poldrack RA
为了克服不健康的行为，一个人必须能够做出更好的选择。改变食物偏好是应对肥胖流行病及其伴随的公共卫生风险的重要战略。然而，人们对食物偏好如何受到有效影响以及什么神经系统支持这种变化知之甚少。在这项研究中，我们研究了一种新的广泛的训练模式，参与者从特定的美味垃圾食品中选择，并因选择主观价值较低的项目而获得奖励。在稍后的探索阶段，当选择真实的消费时，与未经训练的对相比，参与者在训练的对中更经常选择价值较低的项目。我们在一个独立的参与者样本中复制了行为结果，同时用fMRI扫描他们。我们发现，随着训练的进行，以前与认知控制相关的区域的招募减少，特别是左背外侧前额叶皮层（dlPFC）和双侧顶叶皮层。此外，我们发现，左dlPFC的连接是更大的初级运动区域的训练结束时，选择低价值的项目，需要发挥自我控制，这表明形成了一个更强的刺激反应协会。这些发现表明，通过训练可以影响食物选择，并且这种训练与自上而下的额顶叶控制需求减少有关。结果表明，培训模式可能是有前途的干预措施，以影响真实的世界的食物偏好的基础。
To overcome unhealthy behaviors, one must be able to make better choices. Changing food preferences is an important strategy in addressing the obesity epidemic and its accompanying public health risks. However, little is known about how food preferences can be effectively affected and what neural systems support such changes. In this study we investigated a novel extensive training paradigm where participants chose from specific pairs of palatable junk food items and were rewarded for choosing the items with lower subjective value over higher value ones. In a later probe phase, when choices were made for real consumption, participants chose the lower-valued item more often in the trained pairs compared to untrained pairs. We replicated the behavioral results in an independent sample of participants while they were scanned with fMRI. We found that as training progressed there was decreased recruitment of regions that have been previously associated with cognitive control, specifically left dorsolateral prefrontal cortex (dlPFC) and bilateral parietal cortices. Furthermore, we found that connectivity of the left dlPFC was greater with primary motor regions by the end of training for choices of lower-valued items that required exertion of self-control, suggesting a formation of a stronger stimulus-response association. These findings demonstrate that it is possible to influence food choices through training, and that this training is associated with a decreasing need for top-down frontoparietal control. The results suggest that training paradigms may be promising as the basis for interventions to influence real world food preferences.
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影响因子：
120.7
作者：
Flegal, Katherine M.;Carroll, Margaret D.;Curtin, Lester R.
通讯作者：
Curtin, Lester R.
影响因子：
56.9
作者：
Hare, Todd A.;Camerer, Colin F.;Rangel, Antonio
通讯作者：
Rangel, Antonio
DOI：
10.1111/j.1460-9568.2009.06796.x
发表时间：
2009-06
期刊：
The European journal of neuroscience
影响因子：
--
作者：
Tricomi E;Balleine BW;O'Doherty JP
通讯作者：
O'Doherty JP
影响因子：
5.7
作者：
Van Essen, DC
通讯作者：
Van Essen, DC
DOI：
10.1002/bs.3830090304
发表时间：
1964-01-01
期刊：
BEHAVIORAL SCIENCE
影响因子：
--
作者：
BECKER, GM;DEGROOT, MH;MARSCHAK, J
通讯作者：
MARSCHAK, J