Bio-inspired nanomaterials as novel options for the treatment of cardiovascular disease.
Bio-inspired nanomaterials as novel options for the treatment of cardiovascular disease.
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DOI：
10.1016/j.drudis.2021.01.035
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发表时间：
2021-05
影响因子：
7.4
通讯作者：
McCarthy JR
中科院分区：
文献类型：
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作者：
Bose RJ;Ha K;McCarthy JR
心血管疾病（CVD）及其后遗症长期以来一直是发达国家死亡和残疾的主要原因。虽然与CVD相关的死亡率一直在下降，但在很大程度上是由于新的治疗选择，下降率已经持平。因此，非常需要研究可以增加疗效同时减少不良反应的替代治疗策略。纳米材料已被广泛研究，并已成为肿瘤学治疗和诊断目的的有前途的工具;然而，纳米材料的潜力尚未被广泛探索用于心血管医学。在这篇综述中，我们重点介绍了针对心血管疾病的纳米药物领域的最新进展，特别强调了细胞膜包覆的纳米颗粒（NPs）及其应用。
Cardiovascular disease (CVD) and its sequelae have long been the leading causes of death and disability in the developed world. Although mortality associated with CVD has been decreasing, due in large part to novel therapeutic options, the rate of decrease has flattened. Thus, there is a great need to investigate alternate therapeutic strategies that can increase efficacy while decreasing adverse effects. Nanomaterials have been widely investigated and have emerged as promising tools for both therapeutic and diagnostic purposes in oncology; however, the potential of nanomaterials has not been extensively explored for cardiovascular medicine. In this review, we focus on recent developments in the field of nanomedicines targeted for CVDs, with a special emphasis on cell membrane-coated nanoparticles (NPs) and their applications.
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影响因子：
10
作者：
Cheng, Bill;Toh, Elsie K. W.;Hsieh, Patrick C. H.
通讯作者：
Hsieh, Patrick C. H.
影响因子：
168.9
作者：
Chakravarty, Tarun;Sondergaard, Lars;Makkar, Raj R.
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Makkar, Raj R.
影响因子：
16
作者：
Cocozza F;Névo N;Piovesana E;Lahaye X;Buchrieser J;Schwartz O;Manel N;Tkach M;Théry C;Martin-Jaular L
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Martin-Jaular L
影响因子：
2.7
作者：
Baraniak PR;McDevitt TC
通讯作者：
McDevitt TC
一种吸收孔形成毒素的仿生纳米质体。
影响因子：
38.3
作者：
通讯作者：
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