Large moderately-differentiated ovarian Sertoli-Leydig cell tumor in a 13-year-old female: A case report.

Large moderately-differentiated ovarian Sertoli-Leydig cell tumor in a 13-year-old female: A case report.
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一名 13 岁女性的大型中分化卵巢支持间质细胞瘤:病例报告。

DOI:
10.3892/ol.2015.3979
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发表时间:
2016-02
期刊:
影响因子:
2.9
通讯作者:
Yulan Mu
Yulan Mu
中科院分区:
医学4区
文献类型:
--
作者:
Jing Hao;Chunyan Li;Tao Li;Yulan Mu

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卵巢支持-间质细胞瘤,也称为雄母细胞瘤,是一种罕见的卵巢性索间质肿瘤。该肿瘤占所有原发性卵巢肿瘤的<0.5%。支持-间质细胞瘤的临床体征和症状可能与激素产生或占位性病变的存在有关。在目前的研究中,一名13岁的女性在腹痛和腹胀后被诊断为Ic期卵巢支持-间质细胞瘤。右侧卵巢切除术后一个月,随访磁共振成像扫描显示肿瘤残留或复发为阴性。中等分化(2级)和低分化(3级)支持-间质细胞瘤的总体5年生存率为80%,因此强烈建议对该患者进行长期随访。
Sertoli-Leydig cell tumor of the ovary, also known as androblastoma, is a rare neoplasm from the group of sex cord-stromal tumors of the ovary. The tumor accounts for <0.5% of all primary ovarian neoplasms. The clinical signs and symptoms of Sertoli-Leydig cell tumors can be associated with either hormonal production or the presence of a mass-occupying lesion. In the current study, a 13-year-old female was diagnosed with a stage Ic ovarian Sertoli-Leydig cell tumor following abdominal pain and distension. One month after a right oophorectomy, the follow-up magnetic resonance imaging scan was negative for residual or recurrent tumor. The overall 5-year survival rate for moderately-differentiated (grade 2) and poorly-differentiated (grade 3) Sertoli-Leydig cell tumors is 80%, and long-term follow-up is therefore highly advised in this patient.
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