Analysis of protein conformation and dynamics by hydrogen/deuterium exchange MS.

Analysis of protein conformation and dynamics by hydrogen/deuterium exchange MS.
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氢/氘交换MS对蛋白质构象和动力学的分析。

DOI:
10.1021/ac901154s
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发表时间:
2009-10-01
影响因子:
7.4
通讯作者:
Engen, John R.
Engen, John R.
中科院分区:
化学1区
文献类型:
--
作者:
Engen, John R.

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最近的技术进步氢交换MS导致该技术分析蛋白质的形状和运动的能力的改进。东北大学的John Engen提供了该领域急需的最新信息。该封面由Engen制作,展示了蛋白质在H2O/D2 O溶液中“游泳”,背景是样本质谱。
Recent technological advances hydrogen exchange MS have led to improvements in the technique’s ability to analyze the shape and movements of proteins. John Engen of Northeastern University gives a much needed update on the field. The cover, created by Engen, shows proteins “swimming” in an H2O/D2O solution with a sample mass spectrum in the background.
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