Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine.
Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine.
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DOI：
10.1016/j.jep.2011.08.016
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发表时间：
2011-10-31
影响因子：
5.4
通讯作者：
Ding H
中科院分区：
文献类型：
--
作者：
Shang X;Pan H;Li M;Miao X;Ding H
忍冬（Lonicera japonica）在中国已经使用了数千年。现在，已经分离出140多种化合物；研究表明金银花具有广泛的药理作用。同时还可作为保健食品、观赏地被植物等。金银花；（Caprifoliaceae）是一种广泛使用的中药，被称为金银花、仁东和日本金银花。用于治疗外源性风热、流行性温病、疮痈及部分感染性疾病。同时，金银花还可作为保健食品、化妆品、观赏地被植物等。本文综述了金银花的民族药理学、生物活性、毒理学和植物化学等方面的研究进展。通过互联网（谷歌Scholar、百度Scholar、Elsevier、ACS、Medline Plus、CNKI和Web of Science）和图书馆收集金银花的信息。此外，还从一些地方书籍和优秀学者那里获得了有关民族药理学的资料。已分离到140多种化合物，主要成分为精油、有机酸和黄酮等。金银花及其活性成分具有广泛的药理作用，如抗炎、抗菌、抗病毒、抗氧化和保肝等。金银花作为一种重要的中药，对其进一步的研究可以为多种疾病的治疗提供新的药物和疗法，如何更好地利用金银花值得重视。
Lonicera japonica has been used for thousands of years in China. Now, more than 140 chemical compounds have been isolated; and studies show Lonicera japonica possesses wide pharmacological actions. Meanwhile, it could be used as healthy food, ornamental groundcover, etc. Lonicera japonica Thunb. (Caprifoliaceae), a widely used traditional Chinese medicine, was known as Jin Yin Hua (Chinese: ), Ren Dong and Japanese honeysuckle. It was taken to treat the exopathogenic wind-heat, epidemic febrile diseases, sores, carbuncles and some infectious diseases. At the same time, Lonicera japonica could be used as healthy food, cosmetics, ornamental groundcover, and so on. The present paper reviewed the ethnopharmacology, the biological activities, toxicology and phytochemistry of Lonicera japonica. Information on Lonicera japonica was gathered via the Internet (using Google Scholar, Baidu Scholar, Elsevier, ACS, Medline Plus, CNKI and Web of Science) and libraries. Additionally, information also was obtained from some local books and brilliant scholars on ethnopharmacology. More than 140 chemical compounds have been isolated, and the main compositions are essential oils, organic acids and flavones, etc. Lonicera japonica and its active principles possess wide pharmacological actions, such as anti-inflammatory, antibacterial, antiviral, antioxidative and hepatoprotective activities. As an important traditional Chinese medicine, further studies on Lonicera japonica can lead to the development of new drugs and therapeutics for various diseases, and how to utilize it better should be paid more attentions.
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