A comparison of childhood asthma case definitions based on parent-reported data.
A comparison of childhood asthma case definitions based on parent-reported data.
复制标题
基于父母报告数据的儿童哮喘病例定义的比较。
DOI：
10.1016/j.annepidem.2020.10.001
复制
发表时间：
2021-03
影响因子：
5.6
通讯作者：
Camargo CA Jr
中科院分区：
文献类型：
--
作者：
Geller RJ;Espinola JA;Fabiano Filho RC;Hasegawa K;Mansbach JM;Sullivan AF;Camargo CA Jr
根据父母报告的数据比较儿童哮喘的研究定义。我们对921名因毛细支气管炎住院的婴儿进行了一项多中心前瞻性队列研究。通过一年两次的家长访谈进行跟踪调查。哮喘定义是使用父母报告的数据制定的：临床医生按5岁诊断(“广义定义”)；临床医生按5岁诊断4-4.9岁期间有哮喘药物使用或哮喘症状(“流行病学定义”)；临床医生按5岁诊断长期吸入性皮质类固醇使用或4-4.9岁期间有哮喘症状(“严格定义”)；以及流行病学定义中3个标准中的任意两个满足的“灵活定义”。哮喘结果定义使用与已知的主要哮喘危险因素的未调整关联进行评估，并对照子集(n=116)的病历进行验证。广义定义的哮喘患病率为294/875(34%)；流行病学定义为235/859(27%)；严格定义为229/859(27%)；灵活定义为364/826(44%)。风险因素与需要临床医生诊断的定义有类似的强烈关联，而与灵活定义的关联较弱。流行病学和严格的定义具有最高的特异度(96%)和PPV(92%)。临床医生诊断的哮喘的父母报告与已知的哮喘危险因素有很好的相关性。
To compare research definitions of childhood asthma based on parent-reported data. We conducted a multicenter, prospective cohort study of 921 infants hospitalized for bronchiolitis. Follow-up was conducted via biannual parent interviews. Asthma definitions were developed using parent-reported data: clinician diagnosis by age 5 years (“broad definition”); clinician diagnosis by age 5 years with either asthma medication use or asthma symptoms during age 4–4.9 years (“epidemiologic definition”); clinician diagnosis by age 5 years with either long-term inhaled corticosteroid use or asthma symptoms during age 4–4.9 years (“strict definition”); and a “flexible definition” met by any 2 of the 3 criteria in the epidemiologic definition. Asthma outcome definitions were evaluated using unadjusted associations with known major asthma risk factors, and validated against the medical record in a subset (n=116). Asthma prevalence for the broad definition was 294/875 (34%); epidemiologic definition, 235/859 (27%); strict definition, 229/859 (27%); and flexible definition, 364/826 (44%). Risk factors had similarly strong associations with definitions that required clinician diagnosis, and weaker associations with the flexible definition. The epidemiologic and strict definitions had the highest specificity (96%) and PPV (92%). Parent report of clinician-diagnosed asthma correlates well with known asthma risk factors.
登录
查看更多内容
影响因子：
3.7
作者：
Lødrup Carlsen KC;Roll S;Carlsen KH;Mowinckel P;Wijga AH;Brunekreef B;Torrent M;Roberts G;Arshad SH;Kull I;Krämer U;von Berg A;Eller E;Høst A;Kuehni C;Spycher B;Sunyer J;Chen CM;Reich A;Asarnoj A;Puig C;Herbarth O;Mahachie John JM;Van Steen K;Willich SN;Wahn U;Lau S;Keil T;GALEN WP 1.5 ‘Birth Cohorts’ working group
通讯作者：
GALEN WP 1.5 ‘Birth Cohorts’ working group
影响因子：
2.8
作者：
Ma TT;Zhuang Y;Gong HY;Yii AC;Wang XY;Shi HZ
通讯作者：
Shi HZ
影响因子：
2.9
作者：
Cornish RP;Henderson J;Boyd AW;Granell R;Van Staa T;Macleod J
通讯作者：
Macleod J
影响因子：
8
作者：
Ralston, Shawn L.;Lieberthal, Allan S.;Hernandez-Cancio, Sinsi
通讯作者：
Hernandez-Cancio, Sinsi
DOI：
10.5588/ijtld.14.0170
发表时间：
2014-11-01
影响因子：
4
作者：
Asher, I.;Pearce, N.
通讯作者：
Pearce, N.