Neurobiology of Depression as a Comorbidity of Epilepsy.

Neurobiology of Depression as a Comorbidity of Epilepsy.
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DOI:
10.1111/j.1528-1167.2010.02867.x
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发表时间:
2010-12
期刊:
影响因子:
5.6
通讯作者:
Mazarati A
Mazarati A
中科院分区:
医学1区
文献类型:
--
作者:
Sankar R;Mazarati A

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将抑郁症作为人类癫痫合并症的研究受到随之而来的医源性和心理社会变量的限制。为了研究这一临床重要现象的神经生物学,而没有上述混杂因素,我们研究了癫痫相关抑郁症的行为和生物化学相关的两种啮齿动物模型的边缘癫痫。对于该主题的扩展处理,参见牛津大学出版社出版的碧玉的癫痫的基本机制,第四版(Noebels JL,Avoli M,Rogawski MA,Olsen RW,Delgado-Escueta AV,编辑)。可在NCBI Bookshelf上找到。
The study of depression as a comorbidity of epilepsy in humans is limited by the attendant iatrogenic and psychosocial variables. In order to study the neurobiology of this clinically important phenomenon without the above-mentioned confounding factors, we have studied the behavioral and biochemical correlates of epilepsy-associated depression in two rodent models of limbic epileptogenesis. For an expanded treatment of this topic see Jasper’s Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press. Available on NCBI Bookshelf.
实验性颞叶癫痫中血浆皮质酮水平升高和抑郁行为。
DOI: 10.1016/j.nbd.2009.02.018
发表时间: 2009-06
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