Smoking and health-related quality of life in the general population. Independent relationships and large differences according to patterns and quantity of smoking and to gender.

Smoking and health-related quality of life in the general population. Independent relationships and large differences according to patterns and quantity of smoking and to gender.
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DOI:
10.1371/journal.pone.0091562
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Audureau E
Audureau E
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Coste J;Quinquis L;D'Almeida S;Audureau E

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吸烟和健康相关的生活质量(HRQoL)在一般人群之间的关系尚不清楚。量化吸烟模式和HRQoL之间的独立关联,并确定这些关联中的任何阈值或非线性趋势。2003年,对法国一般非机构人口进行了一项全国代表性的横断面家庭调查,其中包括7 525名男子和8 486名妇女,年龄在25-64岁之间。主要结果为医学结局研究36项简表的8个分量表评分。采用线性回归分析评估HRQoL与吸烟史、吸烟量和戒烟之间的相关性,同时控制各种社会经济变量、抑郁症、酒精依赖和病理状况。2013年进行了分析。发现吸烟与HRQoL之间存在独立关联,包括偶尔或轻度吸烟(每天最多5支)的小阳性关联,以及高于此阈值的较大和弥漫性负相关。弱得多的协会和较高的阈值为负HRQoL被发现女性比男性。对于两种性别的前吸烟者,发现HRQoL在戒烟后2至5年内更好。吸烟与HRQoL独立相关,根据吸烟模式和数量以及性别差异较大。这些结果可能有相当大的相关性,公共卫生行动和吸烟者的护理。
Relationships between smoking and health-related quality of life (HRQoL) in the general population remain unclear. To quantify the independent associations between smoking patterns and HRQoL and to identify any threshold or non-linear tendencies in these associations. A national representative, cross-sectional household survey of the French general non institutionalized population included 7525 men and 8486 women, aged 25–64 year in 2003. Scores on the eight subscales of the Medical Outcomes Study 36-item Short Form were the primary outcomes. Linear regression analyses were used to evaluate the associations between HRQoL and smoking history, quantity of smoking and smoking cessation while controlling for various socio-economic variables, depression, alcohol dependence and pathological conditions. Analyses were conducted in 2013. Independent associations between smoking and HRQoL were found, including small positive associations for occasional or light smoking (up to 5 cigarettes per day), and larger and diffuse negative associations above this threshold. Much weaker associations and higher thresholds for negative HRQoL were found for women than for men. For ex-smokers of both genders, HRQoL was found to be better between 2 and 5 years after quitting. Smoking was independently related to HRQoL, with large differences according to the pattern and quantity of smoking, and to gender. These results may have considerable relevance both for public health action and care of smokers.
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