A systematic review of longitudinal studies on the association between depression and smoking in adolescents.

A systematic review of longitudinal studies on the association between depression and smoking in adolescents.
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DOI:
10.1186/1471-2458-9-356
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发表时间:
2009-09-22
期刊:
影响因子:
4.5
通讯作者:
Rehm J
Rehm J
中科院分区:
医学2区
文献类型:
--
作者:
Chaiton MO;Cohen JE;O'Loughlin J;Rehm J

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青少年吸烟与抑郁症之间存在关联,这一点已得到公认,但这种关联的时间顺序仍存在争议。从PubMed、奥维德和PsychInfo数据库中选择1990年1月至2008年7月发表的报告吸烟对非临床人群(13-19岁)抑郁症发病的英语纵向研究。提取研究特征。采用随机效应的荟萃分析合并程序。保留了15项研究进行分析。6项研究中吸烟预测抑郁症的汇总估计值为1.73(95%CI:1.32,2.40; p < 0.001)。12项研究中抑郁症预测吸烟的汇总估计值为1.41(95% CI:1.21,1.63; p < 0.001)。使用抑郁症临床测量的研究更有可能报告双向效应,抑郁症预测吸烟的效果更强。纵向研究的证据表明,吸烟和抑郁症之间的联系是双向的。为了更好地估计这些影响,未来的研究应该考虑以下潜在效用:(a)更短的调查间隔和更长的随访时间,(B)更准确的抑郁测量,(c)充分控制混杂因素。
It is well-established that smoking and depression are associated in adolescents, but the temporal ordering of the association is subject to debate. Longitudinal studies in English language which reported the onset of smoking on depression in non clinical populations (age 13-19) published between January 1990 and July 2008 were selected from PubMed, OVID, and PsychInfo databases. Study characteristics were extracted. Meta-analytic pooling procedures with random effects were used. Fifteen studies were retained for analysis. The pooled estimate for smoking predicting depression in 6 studies was 1.73 (95% CI: 1.32, 2.40; p < 0.001). The pooled estimate for depression predicting smoking in 12 studies was 1.41 (95% CI: 1.21, 1.63; p < 0.001). Studies that used clinical measures of depression were more likely to report a bidirectional effect, with a stronger effect of depression predicting smoking. Evidence from longitudinal studies suggests that the association between smoking and depression is bidirectional. To better estimate these effects, future research should consider the potential utility of: (a) shorter intervals between surveys with longer follow-up time, (b) more accurate measurement of depression, and (c) adequate control of confounding.
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