Frontal theta is a signature of successful working memory manipulation.
Frontal theta is a signature of successful working memory manipulation.
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DOI:
10.1007/s00221-012-3305-3
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发表时间:
2013-01
影响因子:
2
通讯作者:
Aron, Adam R.
中科院分区:
文献类型:
--
作者:
Itthipuripat, Sirawaj;Wessel, Jan R.;Aron, Adam R.
It has been proposed that working memory (WM) is updated/manipulated via a fronto-basal-ganglia circuit. One way that this could happen is via the synchronization of neural oscillations. A first step towards testing this hypothesis is to clearly establish a frontal scalp EEG signature of WM manipulation. Although many EEG studies have indeed revealed frontal EEG signatures for WM, especially in the theta frequency band (3–8 Hz), few of them required subjects to manipulate WM, and of those that did, none specifically tied the EEG signature to the manipulation process per se. Here we employed a WM manipulation task that has been shown with imaging to engage the prefrontal cortex and the striatum. We adapted this task to titrate the success of WM manipulation to approximately 50%. Using time-frequency analysis of EEG, we showed that theta power is increased over frontal cortex for successful versus failed WM manipulation, specifically at the time of the manipulation event. This establishes a clear-cut EEG signature of WM manipulation. Future studies could employ this to test the fronto-basal-ganglia hypothesis of WM updating/manipulation.
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DOI:
10.1523/jneurosci.0828-11.2011
发表时间:
2011-07-27
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
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通讯作者:
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影响因子:
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DOI:
10.1111/j.1460-9568.2010.07217.x
发表时间:
2010-05
期刊:
The European journal of neuroscience
影响因子:
--
作者:
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通讯作者:
Yamaguchi Y
影响因子:
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