Outcomes of Lower Extremity Endovascular Revascularization: Potential Predictors and Prevention Strategies.
Outcomes of Lower Extremity Endovascular Revascularization: Potential Predictors and Prevention Strategies.
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DOI：
10.3390/ijms22042002
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发表时间：
2021-02-18
影响因子：
5.6
通讯作者：
Flex A
中科院分区：
文献类型：
--
作者：
Biscetti F;Nardella E;Rando MM;Cecchini AL;Gasbarrini A;Massetti M;Flex A
外周动脉疾病（PAD）是动脉粥样硬化的一种表现，可影响下肢动脉。最危险的PAD并发症是慢性肢体威胁性缺血（CLTI）。如果不进行血运重建，CLTI通常会导致肢体丧失。然而，无论是开放手术血运重建还是血管内治疗（EVT）都不能确保长期成功和免于再狭窄和血运重建失败。近年来，EVT在所有血管专科中获得了越来越多的认可，成为CLTI患者血运重建的主要方法。在临床实践中，患有相似合并症的患者接受相同手术（在血运重建技术和疾病定位方面）后EVT的不同临床结局导致需要解决的未解决问题。目前，血管重建失败的风险管理是血管领域的主要挑战之一。本文献综述的目的是确定下肢血管内血运重建结局的潜在预测因素和可能的预防策略。
Peripheral artery disease (PAD) is a manifestation of atherosclerosis, which may affect arteries of the lower extremities. The most dangerous PAD complication is chronic limb-threatening ischemia (CLTI). Without revascularization, CLTI often causes limb loss. However, neither open surgical revascularization nor endovascular treatment (EVT) ensure long-term success and freedom from restenosis and revascularization failure. In recent years, EVT has gained growing acceptance among all vascular specialties, becoming the primary approach of revascularization in patients with CLTI. In clinical practice, different clinical outcomes after EVT in patients with similar comorbidities undergoing the same procedure (in terms of revascularization technique and localization of the disease) cause unsolved issues that need to be addressed. Nowadays, risk management of revascularization failure is one of the major challenges in the vascular field. The aim of this literature review is to identify potential predictors for lower extremity endovascular revascularization outcomes and possible prevention strategies.
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