The RIKEN integrated database of mammals.
The RIKEN integrated database of mammals.
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DOI：
10.1093/nar/gkq1078
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发表时间：
2011-01
影响因子：
14.9
通讯作者：
Toyoda T
中科院分区：
文献类型：
--
作者：
Masuya H;Makita Y;Kobayashi N;Nishikata K;Yoshida Y;Mochizuki Y;Doi K;Takatsuki T;Waki K;Tanaka N;Ishii M;Matsushima A;Takahashi S;Hijikata A;Kozaki K;Furuichi T;Kawaji H;Wakana S;Nakamura Y;Yoshiki A;Murata T;Fukami-Kobayashi K;Mohan S;Ohara O;Hayashizaki Y;Mizoguchi R;Obata Y;Toyoda T
理研综合哺乳动物数据库（http://scinets.org/db/mammal）是由理研所推动的多个大型项目所产生的哺乳动物数据库的官方整合项目。该数据库不仅集成了RIKEN的原始数据库，如FANTOM、ENU诱变计划、RIKEN小脑发育转录组数据库和生物资源数据库，而且还从公共数据库导入数据，如Ensembl、MGI和生物医学本体。我们的集成数据库已经在数据库出版媒介的基础设施上实现，称为sciet / scies，或科学家网络系统，其中数据和元数据被构建为语义网，并以各种标准化格式下载。基于本体的哺乳动物相关数据顶层实现直接集成了现有数据库中的代表性知识和单个数据记录，保证了高级的跨数据库搜索，减少了数据管理操作的不均匀性。通过该数据库的开发，我们提出了一种对多数据库异构数据集进行标准化综合管理的新方法，以提高生物医学信息数据的可持续性、可及性、实用性和公共性。
The RIKEN integrated database of mammals (http://scinets.org/db/mammal) is the official undertaking to integrate its mammalian databases produced from multiple large-scale programs that have been promoted by the institute. The database integrates not only RIKEN’s original databases, such as FANTOM, the ENU mutagenesis program, the RIKEN Cerebellar Development Transcriptome Database and the Bioresource Database, but also imported data from public databases, such as Ensembl, MGI and biomedical ontologies. Our integrated database has been implemented on the infrastructure of publication medium for databases, termed SciNetS/SciNeS, or the Scientists’ Networking System, where the data and metadata are structured as a semantic web and are downloadable in various standardized formats. The top-level ontology-based implementation of mammal-related data directly integrates the representative knowledge and individual data records in existing databases to ensure advanced cross-database searches and reduced unevenness of the data management operations. Through the development of this database, we propose a novel methodology for the development of standardized comprehensive management of heterogeneous data sets in multiple databases to improve the sustainability, accessibility, utility and publicity of the data of biomedical information.
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本体论的实际应用在注释和分析大规模的原始小鼠表型数据。
影响因子：
3
作者：
Beck T;Morgan H;Blake A;Wells S;Hancock JM;Mallon AM
通讯作者：
Mallon AM
DOI：
10.1142/s0219720007003168
发表时间：
2007-12-01
影响因子：
1
作者：
Masuya, Hiroshi;Yoshikawa, Sumi;Shiroishi, Toshihiko
通讯作者：
Shiroishi, Toshihiko
影响因子：
2.5
作者：
Hancock, John M.;Mallon, Ann-Marie;Beck, Tim;Gkoutos, Georgios V.;Mungall, Chris;Schofield, Paul N.
通讯作者：
Schofield, Paul N.
影响因子：
12.3
作者：
Mungall CJ;Gkoutos GV;Smith CL;Haendel MA;Lewis SE;Ashburner M
通讯作者：
Ashburner M
影响因子：
4.9
作者：
Makita, Yuko;Kobayashi, Norio;Toyoda, Tetsuro
通讯作者：
Toyoda, Tetsuro