Male Hamster Reproductive Endocrinology

Male Hamster Reproductive Endocrinology
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雄性仓鼠生殖内分泌学

DOI:
10.1007/978-1-4757-0815-8_4
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发表时间:
1985
影响因子:
--
通讯作者:
A. Bartke
A. Bartke
中科院分区:
--
文献类型:
--
作者:
A. Bartke

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男性生殖功能受垂体和睾丸分泌的激素调节。垂体前叶主要通过分泌两种糖蛋白激素来控制睾丸的生长和功能:黄体生成素(LH)和卵泡刺激素(FSH)。黄体生成素与睾丸间质中的间质细胞结合,并刺激与类固醇产生相关的多个过程。这导致睾丸分泌雄激素类固醇(主要是睾酮)增加。卵泡刺激激素与睾丸曲细精管中的支持细胞结合并刺激其分泌活动,这对于生殖细胞增殖和分化的正常进行至关重要,从而导致精子的产生。在啮齿类动物中,垂体对睾丸的控制还涉及催乳素 (PRL),这是一种与 Leydig 细胞结合并调节 LH 受体数量的蛋白质激素。哺乳动物睾丸产生的主要雄激素类固醇是睾酮。睾酮在男性生殖生理的调节中起着关键作用,因为它几乎控制着生殖和性功能的所有方面,包括精子发生、附睾中精子的成熟、男性副生殖腺的生长及其产生精浆的能力,以及领地、攻击和交配行为。
Male reproductive functions are regulated by hormones secreted by the pituitary and by the testis. The anterior pituitary controls testicular growth and function primarily by secreting two glycoprotein hormones: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Luteinizing hormone binds to Leydig cells in the testicular interstitium and stimulates several processes related to steroid production. This results in increased secretion of androgenic steroids, primarily testosterone, by the testis. Follicle-stimulating hormone binds to Sertoli cells in the seminiferous tubules of the testis and stimulates their secretory activity, which is essential for the normal progression of multiplication and differentiation of germ cells, leading to the production of spermatozoa. In rodents, pituitary control of the testis also involves prolactin (PRL), a protein hormone that binds to Leydig cells and regulates the number of LH receptors. The principal androgenic steroid produced by the mammalian testis is testosterone. Testosterone plays a pivotal role in the regulation of male reproductive physiology since it controls virtually all aspects of reproductive and sexual functions, including spermatogenesis, maturation of spermatozoa in the epididymis, growth of male accessory reproductive glands and their ability to produce seminal plasma, as well as territorial, aggressive, and copulatory behavior.
DOI: 10.1371/journal.pone.0054482
发表时间: 2013
期刊: PloS one
影响因子: 3.7
作者:
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雄性仓鼠生殖系统的衰老:行为和内分泌模式。
DOI: 10.1095/biolreprod26.5.791
发表时间: 1982
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光周期期间神经内分泌功能的改变导致金黄地鼠睾丸萎缩和复发。
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发表时间: 1982
影响因子: 3.6
作者:
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睾酮、孕烯醇酮、黄体酮和皮质醇对短光周期引起性腺萎缩的雄性金仓鼠垂体和睾丸功能的影响。
DOI: 10.1677/joe.0.0900097
发表时间: 1981
期刊: The Journal of endocrinology
影响因子: --
作者:
Bartke,A;Klemcke,H;Amador,A
通讯作者: Amador,A
DOI: 10.1210/endo-108-1-133
发表时间: 1981
期刊: Endocrinology
影响因子: 4.8
作者:
Bartke,A;Siler-Khodr,TM;Hogan,MP;Roychoudhury,P
通讯作者: Roychoudhury,P