Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People.
Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People.
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DOI：
10.1093/ageing/afq034
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发表时间：
2010-07
期刊：
影响因子：
6.7
通讯作者：
European Working Group on Sarcopenia in Older People
中科院分区：
文献类型：
--
作者：
Cruz-Jentoft AJ;Baeyens JP;Bauer JM;Boirie Y;Cederholm T;Landi F;Martin FC;Michel JP;Rolland Y;Schneider SM;Topinková E;Vandewoude M;Zamboni M;European Working Group on Sarcopenia in Older People
欧洲老年人肉质疏松症工作组(EWGSOP)为年龄相关性骨质疏松症制定了一个实用的临床定义和共识诊断标准。EWGSOP包括来自四个参与组织的代表，即欧洲老年医学会、欧洲临床营养和代谢学会、国际老年学和老年医学协会-欧洲地区以及国际营养和老龄协会。这些组织认可了最终文件中的调查结果。该小组讨论并解决了以下问题，使用医学文献建立了基于证据的答案：(I)什么是石棺减少症？(Ii)定义石棺减少的参数是什么？(3)哪些变量反映了这些参数，可以使用哪些测量工具和分界点？(4)骨质症与恶病质、虚弱和骨质型肥胖有何关系？对于骨质疏松症的诊断，EWGSOP建议同时使用低肌肉质量和低肌肉功能(力量或表现)的存在。EWGSOP以不同的方式应用这些特征来进一步将概念性阶段定义为“降温前期”、“降温”和“严重降温”。EWGSOP回顾了一系列可用于测量肌肉质量、肌肉力量和身体表现的具体变量的工具。我们的论文总结了目前可用的数据，根据年龄和性别定义了骨质疏松症的分界点；建议了一种基于步态速度、握力和肌肉质量的测量来发现老年人骨质疏松症病例的算法；并提出了建议的主要和次要结果领域的列表，以供研究。一旦骨质疏松症的手术定义被采纳并纳入综合老年医学评估的主流，下一步就是定义骨质疏松症的自然病程，并开发和定义有效的治疗方法。
The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia. EWGSOP included representatives from four participant organisations, i.e. the European Geriatric Medicine Society, the European Society for Clinical Nutrition and Metabolism, the International Association of Gerontology and Geriatrics—European Region and the International Association of Nutrition and Aging. These organisations endorsed the findings in the final document. The group met and addressed the following questions, using the medical literature to build evidence-based answers: (i) What is sarcopenia? (ii) What parameters define sarcopenia? (iii) What variables reflect these parameters, and what measurement tools and cut-off points can be used? (iv) How does sarcopenia relate to cachexia, frailty and sarcopenic obesity? For the diagnosis of sarcopenia, EWGSOP recommends using the presence of both low muscle mass + low muscle function (strength or performance). EWGSOP variously applies these characteristics to further define conceptual stages as ‘presarcopenia’, ‘sarcopenia’ and ‘severe sarcopenia’. EWGSOP reviewed a wide range of tools that can be used to measure the specific variables of muscle mass, muscle strength and physical performance. Our paper summarises currently available data defining sarcopenia cut-off points by age and gender; suggests an algorithm for sarcopenia case finding in older individuals based on measurements of gait speed, grip strength and muscle mass; and presents a list of suggested primary and secondary outcome domains for research. Once an operational definition of sarcopenia is adopted and included in the mainstream of comprehensive geriatric assessment, the next steps are to define the natural course of sarcopenia and to develop and define effective treatment.
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DOI：
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发表时间：
2009-01
影响因子：
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DOI：
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影响因子：
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