The response to inositol: regulation of glycerolipid metabolism and stress response signaling in yeast.

The response to inositol: regulation of glycerolipid metabolism and stress response signaling in yeast.
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DOI:
10.1016/j.chemphyslip.2013.12.013
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发表时间:
2014-05
影响因子:
3.4
通讯作者:
Jesch SA
Jesch SA
中科院分区:
生物学3区
文献类型:
--
作者:
Henry SA;Gaspar ML;Jesch SA

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This article focuses on discoveries of the mechanisms governing the regulation of glycerolipid metabolism and stress response signaling in response to the phospholipid precursor, inositol. The regulation of glycerolipid lipid metabolism in yeast in response to inositol is highly complex, but increasingly well understood, and the roles of individual lipids in stress response are also increasingly well characterized. Discoveries that have emerged over several decades of genetic, molecular and biochemical analyses of metabolic, regulatory and signaling responses of yeast cells, both mutant and wild type, to the availability of the phospholipid precursor, inositol are discussed.
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