Density-constrained Chemotaxis and Hele-Shaw flow

Density-constrained Chemotaxis and Hele-Shaw flow
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密度约束趋化性和 Hele-Shaw 流

DOI:
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发表时间:
2022
期刊:
影响因子:
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通讯作者:
Yijing Wu
Yijing Wu
中科院分区:
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作者:
Inwon C. Kim;A. Mellet;Yijing Wu

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.我们考虑一个具有趋化性的拥塞动力学模型,其中细胞的密度遵循它产生的化学信号,同时观察不可压缩性约束。我们表明,当化学扩散缓慢,吸引细胞强烈,那么拥挤的细胞的动态是很好地近似由表面张力驱动的自由边界问题。更准确地说,我们表明,在这个极限的细胞密度收敛到一组的特征函数,其演变是由Hele-Shaw自由边界问题与表面张力。我们的问题是设置在一个有界的区域,这导致了一个有趣的分析的极限边界条件的密度函数。也就是说,我们证明了罗宾边界条件的化学势的假设导致接触角条件的自由界面。
. We consider a model of congestion dynamics with chemotaxis, where the density of cells follows the chemical signal it generates, while observing an incompressibility constraint. We show that when the chemical diffuses slowly and attracts the cells strongly, then the dynamics of the congested cells is well approximated by a surface-tension driven free boundary problem. More precisely, we show that in this limit the density of cell converges to the characteristic function of a set whose evolution is described by a Hele-Shaw free boundary problem with surface tension. Our problem is set in a bounded domain, which leads to an interesting analysis on the limiting boundary conditions for the density function. Namely, we prove that the assumption of Robin boundary conditions for the chemical potential leads to a contact angle condition for the free interface.
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