The Role of Uncontrollable Trauma in the Development of PTSD and Alcohol Addiction

The Role of Uncontrollable Trauma in the Development of PTSD and Alcohol Addiction
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无法控制的创伤在创伤后应激障碍和酒精成瘾发展中的作用

DOI:
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发表时间:
1999
期刊:
Alcohol Research and Health
影响因子:
--
通讯作者:
D. Bux
D. Bux
中科院分区:
--
文献类型:
--
作者:
J. Volpicelli;G. Balaraman;J. Hahn;H. Wallace;D. Bux

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在创伤事件之后,人们经常报告使用酒精来缓解他们的焦虑,易怒和抑郁症状。酒精可以缓解这些症状,因为饮酒可以弥补创伤经历后内啡肽活性的不足。在几分钟内暴露于创伤事件有一个增加的水平内啡肽在大脑中。在创伤期间,内啡肽水平保持升高,有助于麻木创伤的情感和身体疼痛。然而,创伤结束后,内啡肽水平逐渐下降,这可能导致内啡肽戒断期,可持续数小时至数天。内啡肽的这段时间可能会产生情绪困扰,并导致创伤后应激障碍(PTSD)的其他症状。由于饮酒会增加内啡肽的活性,因此创伤后饮酒可以用来补偿内啡肽的减少,从而避免相关的情绪困扰。这一模型对创伤后应激障碍和酗酒的治疗具有重要意义。
After a traumatic event, people often report using alcohol to relieve their symptoms of anxiety, irritability, and depression. Alcohol may relieve these symptoms because drinking compensates for deficiencies in endorphin activity following a traumatic experience. Within minutes of exposure to a traumatic event there is an increase in the level of endorphins in the brain. During the time of the trauma, endorphin levels remain elevated and help numb the emotional and physical pain of the trauma. However, after the trauma is over, endorphin levels gradually decrease and this may lead to a period of endorphin withdrawal that can last from hours to days. This period of endorphin withdrawal may produce emotional distress and contribute to other symptoms of posttraumatic stress disorder (PTSD). Because alcohol use increases endorphin activity, drinking following trauma may be used to compensate this endorphin withdrawal and thus avoid the associated emotional distress. This model has important implications for the treatment of PTSD and alcoholism.
DOI: 10.1001/archpsyc.1995.03950240066012
发表时间: 1995-12-01
影响因子: --
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