Impact of poor-quality medicines in the 'developing' world.

Impact of poor-quality medicines in the 'developing' world.
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DOI:
10.1016/j.tips.2009.11.005
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发表时间:
2010-03
影响因子:
13.8
通讯作者:
Fernández FM
Fernández FM
中科院分区:
医学1区
文献类型:
--
作者:
Newton PN;Green MD;Fernández FM

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自从几千年前我们的祖先开始交易以来,假药和不合格药品一直是一个反复出现的问题,历史上不时出现抗微生物药物供应危机,比如17世纪的假金鸡纳树皮和19世纪的假奎宁。不幸的是,这个问题仍然存在,特别是在“发展中”国家,毫无戒心的病人受到了折磨。劣质药品是一个重要的(但被忽视的)公共卫生问题。它们在治疗研究和决策方面的巨大努力与高质量药物的实施之间造成了“裂缝”。
Since our ancestors began trading several millennia ago, counterfeit and substandard medicines have been a recurring problem, with history punctuated by crises in the supply of anti-microbials, such as fake cinchona bark in the 1600s and fake quinine in the 1800s. Unfortunately this problem persists, in particular afflicting unsuspecting patients in ‘developing’ countries. Poor-quality drugs are a vital (but neglected) public health problem. They contribute to a ‘crevasse’ between the enormous effort in therapeutic research and policy decisions and implementation of good-quality medicines.
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