Discrimination and systemic inflammation: A critical review and synthesis.

Discrimination and systemic inflammation: A critical review and synthesis.
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DOI:
10.1016/j.bbi.2020.07.017
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发表时间:
2020-10
期刊:
Brain, behavior, and immunity
影响因子:
--
通讯作者:
Williams DR
Williams DR
中科院分区:
其他
文献类型:
--
作者:
Cuevas AG;Ong AD;Carvalho K;Ho T;Chan SWC;Allen JD;Chen R;Rodgers J;Biba U;Williams DR

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遭受歧视或不公平待遇已成为疾病的一个重要风险因素,对种族和族裔少数群体的影响尤为严重。歧视性经历可能像其他压力源一样起作用,因为它们激活了对维持内稳态产生不利影响的生理反应。研究表明,炎症在应激相关疾病的病理生理学中起着关键作用。歧视和炎症的最新研究结果进行了讨论。我们强调了目前证据的局限性,并为未来寻求研究歧视与炎症之间关系的研究提供了建议。
Exposure to discrimination or unfair treatment has emerged as an important risk factor for illness and disease that disproportionately affects racial and ethnic minorities. Discriminatory experiences may operate like other stressors in that they activate physiological responses that adversely affect the maintenance of homeostasis. Research suggests that inflammation plays a critical role in the pathophysiology of stress-related diseases. Recent findings on discrimination and inflammation are discussed. We highlight limitations in the current evidence and provide recommendations for future studies that seek to examine the association between discrimination and inflammation.
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