MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction.
MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction.
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MCDB:一个综合性的有丝分裂灾难数据库,用于检索、蛋白质序列比对和目标预测
DOI:
10.1016/j.apsb.2021.05.032
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发表时间:
2021-10
期刊:
影响因子:
--
通讯作者:
Ouyang L
中科院分区:
文献类型:
--
作者:
Zhang L;Zhang L;Guo Y;Xiao M;Feng L;Yang C;Wang G;Ouyang L
Mitotic catastrophe (MC) is a form of programmed cell death induced by mitotic process disorders, which is very important in tumor prevention, development, and drug resistance. Because rapidly increased data for MC is vigorously promoting the tumor-related biomedical and clinical study, it is urgent for us to develop a professional and comprehensive database to curate MC-related data. Mitotic Catastrophe Database (MCDB) consists of 1214 genes/proteins and 5014 compounds collected and organized from more than 8000 research articles. Also, MCDB defines the confidence level, classification criteria, and uniform naming rules for MC-related data, which greatly improves data reliability and retrieval convenience. Moreover, MCDB develops protein sequence alignment and target prediction functions. The former can be used to predict new potential MC-related genes and proteins, and the latter can facilitate the identification of potential target proteins of unknown MC-related compounds. In short, MCDB is such a proprietary, standard, and comprehensive database for MC-relate data that will facilitate the exploration of MC from chemists to biologists in the fields of medicinal chemistry, molecular biology, bioinformatics, oncology and so on. The MCDB is distributed on http://www.combio-lezhang.online/MCDB/index_html/. MCDB is a proprietary, standard, and comprehensive database for mitotic catastrophe (MC)-relate data that will facilitate the exploration of MC from chemists to biologists in the fields of medicinal chemistry, molecular biology, bioinformatics, oncology and so on.
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影响因子:
14.9
作者:
The Gene Ontology Consortium
通讯作者:
The Gene Ontology Consortium
影响因子:
8.5
作者:
Deng, Yiqi;Zhu, Lingjuan;Liu, Bo
通讯作者:
Liu, Bo
DOI:
10.1021/ci9803381
发表时间:
1999-07-01
期刊:
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
影响因子:
--
作者:
Butina, D
通讯作者:
Butina, D
影响因子:
6.6
作者:
Drápela S;Khirsariya P;van Weerden WM;Fedr R;Suchánková T;Búzová D;Červený J;Hampl A;Puhr M;Watson WR;Culig Z;Krejčí L;Paruch K;Souček K
通讯作者:
Souček K
影响因子:
8.6
作者:
Bajusz D;Rácz A;Héberger K
通讯作者:
Héberger K