Yoga for breast cancer patients and survivors: a systematic review and meta-analysis.

Yoga for breast cancer patients and survivors: a systematic review and meta-analysis.
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DOI:
10.1186/1471-2407-12-412
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发表时间:
2012-09-18
期刊:
影响因子:
3.8
通讯作者:
Dobos G
Dobos G
中科院分区:
医学2区
文献类型:
--
作者:
Cramer H;Lange S;Klose P;Paul A;Dobos G

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许多乳腺癌患者和幸存者使用瑜伽来应对他们的疾病。这篇综述的目的是系统地评估和荟萃分析瑜伽对乳腺癌患者和幸存者的健康相关生活质量和心理健康影响的证据。Medline、SqucINFO、EMBASE、CAMBASE和Cochrane图书馆都进行了筛选,直到2012年2月。在评估乳腺癌患者或幸存者的健康相关生活质量或心理健康时,分析了将瑜伽与对照组进行比较的随机对照试验(RCT)。使用Cochrane偏差风险工具评估偏差风险。计算标准化均数差(SMD)和95%可信区间(CI)。共纳入12项随机对照试验,共有742名参与者。7个随机对照试验将瑜伽与不治疗相比较;3个随机对照试验将瑜伽与支持性疗法相比较;1个随机对照试验将瑜伽与健康教育相比较;1个随机对照试验将物理疗法和瑜伽的组合与单独的物理疗法进行比较。有证据表明,与全球健康相关的生活质量(SMD = 0.62[95%CI:0.04至1.21];P = 0.04)、功能(SMD = 0.30[95%CI:0.03至0.57)、社交(SMD = 0.29[95%CI:0.08至0.50];P < 0.01)和精神健康(SMD = 0.41[95%CI:0.08;0.74];P = .01)。然而,这些影响只存在于选择偏向风险不明确或风险很高的研究中。对心理健康的短期影响也被发现:焦虑(SMD = −1.51[95%CI:-2.47;-0.55];P < 0.01),抑郁(SMD = −1.59[95%CI:-2.68对−0.51];P < 0.01),感知压力(SMD = −1.14[95%CI:-2.16;-0.12];P = 为0.86[95%CI:-1.5 0;-0.2 2];P < 0.0 1)。亚组分析显示,瑜伽仅在癌症积极治疗期间有效,而在积极治疗完成后没有。这项系统的回顾发现了瑜伽在改善乳腺癌患者心理健康方面的短期效果的证据。对健康相关生活质量的短期影响不能与偏见明显区分开来。瑜伽可以被推荐作为一种干预措施,以改善乳腺癌治疗期间的心理健康。
Many breast cancer patients and survivors use yoga to cope with their disease. The aim of this review was to systematically assess and meta-analyze the evidence for effects of yoga on health-related quality of life and psychological health in breast cancer patients and survivors. MEDLINE, PsycInfo, EMBASE, CAMBASE, and the Cochrane Library were screened through February 2012. Randomized controlled trials (RCTs) comparing yoga to controls were analyzed when they assessed health-related quality of life or psychological health in breast cancer patients or survivors. Risk of bias was assessed using the Cochrane risk of bias tool. Standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated. Twelve RCTs with a total of 742 participants were included. Seven RCTs compared yoga to no treatment; 3 RCTs compared yoga to supportive therapy; 1 RCT compared yoga to health education; and 1 RCT compared a combination of physiotherapy and yoga to physiotherapy alone. Evidence was found for short-term effects on global health-related quality of life (SMD = 0.62 [95% CI: 0.04 to 1.21]; P = 0.04), functional (SMD = 0.30 [95% CI: 0.03 to 0.57), social (SMD = 0.29 [95% CI: 0.08 to 0.50]; P < 0.01), and spiritual well-being (SMD = 0.41 [95% CI: 0.08; 0.74]; P = 0.01). These effects were, however, only present in studies with unclear or high risk of selection bias. Short-term effects on psychological health also were found: anxiety (SMD = −1.51 [95% CI: -2.47; -0.55]; P < 0.01), depression (SMD = −1.59 [95% CI: -2.68 to −0.51]; P < 0.01), perceived stress (SMD = −1.14 [95% CI:-2.16; -0.12]; P = 0.03), and psychological distress (SMD = −0.86 [95% CI:-1.50; -0.22]; P < 0.01). Subgroup analyses revealed evidence of efficacy only for yoga during active cancer treatment but not after completion of active treatment. This systematic review found evidence for short-term effects of yoga in improving psychological health in breast cancer patients. The short-term effects on health-related quality of life could not be clearly distinguished from bias. Yoga can be recommended as an intervention to improve psychological health during breast cancer treatment.
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