PML and the oncogenic nuclear domains in regulating transcriptional repression.
PML and the oncogenic nuclear domains in regulating transcriptional repression.
复制标题
PML 和致癌核结构域在调节转录抑制中的作用。
DOI：
10.1016/s0955-0674(00)00144-7
复制
发表时间：
2000
影响因子：
7.5
通讯作者：
Chen,JD
中科院分区：
文献类型：
--
作者：
Li,H;Chen,JD
Promyelocytic leukemia protein (PML) is a tumor suppressor involved in the t(15;17) translocation that causes acute promyelocytic leukemia (APL). PML is located at multiple nuclear domains known as PML oncogenic domains (PODs), whose structures are dynamically regulated and disrupted in t(15;17) APL cells. PML is involved in several important cellular processes; however, its exact function is unclear. Recently, a POD-associated protein was found to be transcriptional repressor, suggesting a new role for PODs in regulating transcriptional repression.
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DOI：
10.1073/pnas.96.6.2627
发表时间：
1999-03-16
影响因子：
11.1
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通讯作者：
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