Asymmetric and symmetric PCR of gold nanoparticles: A pathway to scaled-up self-assembly with tunable chirality
Asymmetric and symmetric PCR of gold nanoparticles: A pathway to scaled-up self-assembly with tunable chirality
复制标题
金纳米粒子的不对称和对称 PCR：具有可调手性的放大自组装途径
DOI：
10.1039/c2jm15800k
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发表时间：
2012-02
影响因子：
--
通讯作者：
Xu Chuanlai
中科院分区：
文献类型：
--
作者：
Zhao Yuan;Xu Liguang;Kuang Hua;Wang Libing;Xu Chuanlai
对纳米材料的许多实际应用来说，可伸缩制备纳米粒子组件和超结构并控制其大小、组成和几何形状是一项挑战。DNA纳米技术既提供了多功能性的粒子排列，也提供了多种途径来实现有趣的光学、电子、生物和催化特性。在这项工作中，我们使用聚合酶链式反应(PCR)从不同大小的金纳米颗粒中产生复杂的超结构。通过控制聚合酶链数和引物浓度，在不对称和对称聚合酶链式反应中组装了两种不同的超结构。随着聚合酶链式反应数目的增加，在35-600 nm范围内的结构尺寸相应增大。更重要的是，放大的GNP超结构表现出可调的手性，这在不对称和对称PCR中显示出明显的差异。从实验和理论两方面分析了手性产生的原因。GNPs的异质性和自组装的构象转变导致了GNP超结构中手性的出现。聚合酶链式反应是可控制备手性超结构的重要工具，其实验和力学研究将极大地促进手性材料制备技术的发展。
Scalable preparation of nanoparticle assemblies and superstructures with control over the size, composition, and geometry represents a challenge for many practical applications of nanomaterials. DNA nanotechnology offers both versatility of particle arrangements and multiple gateways to interesting optical, electronic, biological, and catalytic properties. In this work we used a polymerase chain reaction (PCR) to produce complex superstructures from heterogeneously-sized gold nanoparticles. By controlling the number of PCR cycles and primer density, two distinct superstructures were assembled at asymmetric and symmetric PCR. With the increasing of PCR number, the size of structures was accordingly increased in the range 35–600nm. More importantly, the scaled-up GNP superstructures exhibited tunable chirality, which showed distinct differences between asymmetric and symmetric PCR. The origin of the chirality was analyzed from both an experimental and theoretical point of view. The heterogeneity of GNPs and conformational transition of self-assembly contributed to the occurrence of chirality in the GNP superstructures. PCR could be a very important and potentially useful tool for the controllable preparation of scaled-up superstructures with tunable chirality, and this experimental and mechanical research could significantly promote the technical development of chiral material preparation.
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影响因子：
16.6
作者：
Khanal, Bishnu P.;Zubarev, Eugene R.
通讯作者：
Zubarev, Eugene R.
由纳米颗粒、纳米棒和纳米线轻松合成杂化纳米结构
影响因子：
--
作者：
Mao, Jiayuan Cao, Xueqin Zhen, Junwei Shao, Huilin
通讯作者：
Mao, Jiayuan Cao, Xueqin Zhen, Junwei Shao, Huilin
影响因子：
64.8
作者：
Younan Xia;Byungkwon Lim
通讯作者：
Younan Xia;Byungkwon Lim
DOI：
10.1073/pnas.1016530108
发表时间：
2011-05-17
影响因子：
11.1
作者：
Alvarez-Puebla, Ramon A.;Agarwal, Ashish;Liz-Marzan, Luis M.
通讯作者：
Liz-Marzan, Luis M.
影响因子：
16.6
作者：
Li, QA;Lee, JS;Chang, YT
通讯作者：
Chang, YT