Combination of multichannel single-voxel MRS signals using generalized least squares.

Combination of multichannel single-voxel MRS signals using generalized least squares.
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DOI:
10.1002/jmri.23941
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发表时间:
2013-06
影响因子:
4.4
通讯作者:
Shen, Jun
Shen, Jun
中科院分区:
医学2区
文献类型:
--
作者:
An, Li;van der Veen, Jan Willem;Li, Shizhe;Thomasson, David M.;Shen, Jun

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提出用广义最小二乘(GLS)算法对多通道单体素磁振子信号进行组合。在配备32通道接收线圈的7 T扫描仪上进行了幻影和活体脑MRS实验,并进行了蒙特卡罗模拟,以比较GLS方法与最近报道的两种光谱组合方法的变异系数(CV)。与现有的两种方法相比,GLS方法在模拟、模拟和体内实验中显著降低了CV值。GLS法可以提高峰定量的精度。
To propose using the generalized least square (GLS) algorithm for combining multichannel single-voxel MRS signals. Phantom and in vivo brain MRS experiments on a 7 T scanner equipped with a 32-channel receiver coil, as well as Monte Carlo simulations, were performed to compare the coefficient of variation (CV) of the GLS method with those of two recently reported spectral combination methods. Compared to the two existing methods, the GLS method significantly reduced CV values for the simulation, phantom, and in vivo experiments. The GLS method can lead to improved precision of peak quantification.
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