Social performance is more closely associated with theory of mind and autobiographical memory than with psychopathological symptoms in clinically stable patients with schizophrenia-spectrum disorders
Social performance is more closely associated with theory of mind and autobiographical memory than with psychopathological symptoms in clinically stable patients with schizophrenia-spectrum disorders
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在临床稳定的精神分裂症谱系障碍患者中，社交表现与心理理论和自传体记忆的关系比与精神病理症状的关系更密切
DOI：
10.1016/j.psychres.2009.10.004
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发表时间：
2010
影响因子：
11.3
通讯作者：
Lincoln
中科院分区：
文献类型：
--
作者：
Rief. W;Lüllmann. E;Lincoln
本研究旨在探讨精神病患者心理理论能力（ToM）缺陷、自传体记忆（AM）缺陷与社会表现的关系。此外，该研究旨在调查ToM和AM的缺陷是否比精神病理症状和其他神经认知变量更能预测社会表现。在一个横断面设计中，精神分裂症谱系障碍患者（n=55）和健康对照组（n=45）完成了一个ToM电影范式，其中他们必须推断电影中显示社会情境的角色的意图和情绪，以及一阶和二阶错误信念ToM范式。自传体记忆的回忆采用结构化访谈。社会表现在标准化的角色扮演情境中进行评估，随后由受过训练的评分员进行评分，而诊断是盲目的。AM缺陷与精神分裂症谱系障碍患者推断电影人物意图的能力和社会表现的缺陷有关。心理理论推断电影人物情感的能力和AM的回忆是比精神病理症状和其他神经认知缺陷更好的社会表现预测。结果表明，旨在提高心理理论赤字和赤字AM的干预措施可能会导致社会绩效的改善。
The purpose of this study was to examine the association of deficits in Theory of Mind ability (ToM), deficits in recalling autobiographical memories (AM) and social performance in patients with psychosis. Furthermore, the study aimed to investigate if deficits in ToM and AM are better predictors of social performance than psychopathological symptoms and other neurocognitive variables. In a cross-sectional design, patients with schizophrenia-spectrum disorders (n=55) and healthy controls (n=45) completed a ToM movie paradigm in which they had to infer the characters' intentions and emotions in movies displaying social situations and a first- and second-order false belief ToM paradigm. Recall of autobiographical memories was investigated using a structured interview. Social performance was assessed in a standardized role-play situation, which was later rated by trained raters, blind to diagnosis. Deficits in AM were associated with deficits in the ability to infer intentions of movie characters and in social performance in patients with schizophrenia-spectrum disorders. ToM ability to infer emotions of movie characters and recalling of AM were better predictors of social performance than psychopathological symptoms and other neurocognitive deficits. The results suggest that interventions aiming to enhance ToM deficits and deficits in AM might result in improvement of social performance.
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