Pharmacokinetic Models for Active Learning of Differential Equations
Pharmacokinetic Models for Active Learning of Differential Equations
复制标题
微分方程主动学习的药代动力学模型
DOI:
10.1080/10511970.2018.1484398
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发表时间:
2018
期刊:
影响因子:
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通讯作者:
Agyemang-Barimah, Beulah
中科院分区:
文献类型:
--
作者:
Shelton, Therese;Laurent, Theresa;Agyemang-Barimah, Beulah
We present adaptable activities for models of drug movement in the human body – pharmacokinetics – that motivate the learning of ordinary differential equations with an interdisciplinary topic. Specifically, we model aspirin, caffeine, and digoxin. We discuss the pedagogy of guiding students to understand, develop, and analyze models, progressing in complexity to a system of differential equations. We investigate the effects of parameter values that distinguish various health levels, and dosing that may have toxic effects. Our assignments include modeling in a student-centered, active, and increasingly inquiry-oriented setting through which the mathematics and biology inform and reinforce each other. We include supplemental information regarding inquiry methods, student learning outcomes, a student’s commentary about our activities, and support through mathematical communities such as POGIL and SIMIODE.
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DOI:
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发表时间:
2017
期刊:
影响因子:
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作者:
C. Bénéteau;Zdeňka Guadarrama;Jill E. Guerra;Laura Lenz;J. Lewis;A. Straumanis
通讯作者:
A. Straumanis
DOI:
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发表时间:
2017
期刊:
影响因子:
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作者:
T. Shelton
通讯作者:
T. Shelton
DOI:
10.1007/978-3-642-21852-1_61
发表时间:
2011
期刊:
Food Additives & Contaminants
影响因子:
--
作者:
F. Ritter;Kuo
通讯作者:
Kuo
DOI:
--
发表时间:
2016
期刊:
影响因子:
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作者:
K. Spayd;James G. Puckett
通讯作者:
James G. Puckett
DOI:
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发表时间:
2017
期刊:
影响因子:
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作者:
D. Ernst;Angela M. Hodge;Stan T. Yoshinobu
通讯作者:
Stan T. Yoshinobu